Concept explainers
Achromatopsia is a rare autosomal recessive form of complete color blindness that affects about
Achromatopsia was first recorded on Pingelap in the
Want to see the full answer?
Check out a sample textbook solutionChapter 20 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
- Cystic fibrosis is an autosomal recessive disorder that affects 1 in 3 000 newborns with Caucasian background. It causes thick mucus build up in various organs and can cause damages and problems in respiratory and digestive systems. a) What is the frequency of the cystic fibrosis allele in the Caucasian population? Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places. b) What percentage of the Caucasian population would be carriers for cystic fibrosis? Show all your work and express your answer rounded to two decimal places. c)If two individuals are carriers of the cystic fibrosis allele, what is the probability that they would have a girl without cystic fibrosis? Show all your work (including the Punnett square) and express your answer as a value between 0 and 1 rounded to two decimal places.arrow_forwardHeterozygote advantage is an interesting condition in those individuals who have one of each allele (dominant and recessive) have a higher survival rate than those individuals who are either homozygous dominant or homozygous recessive. Sickle-cell anemia is such a genetic disease associated with the recessive allele. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Thus, many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells that readily collapse when deoxygenated. Although malaria cannot grow in these red blood cells, individuals often die because of the genetic defect. However, individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. In addition, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to…arrow_forwardCystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped the afflicted to live through adulthood. The mother of Claudia died from cystic fibrosis, but her father was normal and never had any relative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that: a. all children will be normal b. at least two will be normal PLEASE SHOW COMPLETE SOLUTIONarrow_forward
- Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped the afflicted to live through adulthood. Betty's mother died from cystic fibrosis, but her father was normal and never had any relative with CF. Her fiancé, Jones, turned out to be a carrier of the CF allele. What are the genotypes of Betty and Jones? 1. Betty: ________________________ 2. Jones: _____________________ They planned to have four children. What is the probability that: 3. all children will be normal 4. at least two will be normalarrow_forwardSickle cell anemia is an autosomal recessive genetic disorder. Because individuals affected bysickle cell anemia have defective hemoglobin proteins, their blood cannot transport oxygenproperly. There appears to be a relationship between the incidence of malaria and sickle cellanemia. Individuals with sickle cell anemia and carriers of the sickle cell allele have someresistance to malaria. Malaria is caused by the parasite Plasmodium and is transmitted amonghumans by mosquitoes.4. If scientists are successful in reducing significantly or eliminating malaria, the best predictionfor what will happen to the allele for sickle cell anemia in the population is that it willa. not be affected by the elimination of malariab. increase as its selective advantage is increasedc. be reduced as its selective advantage is decreasedd. disappear quickly as its selective advantage is increasedarrow_forwardSickle cell anemia is an autosomal recessive genetic disorder. Because individuals affected bysickle cell anemia have defective hemoglobin proteins, their blood cannot transport oxygenproperly. There appears to be a relationship between the incidence of malaria and sickle cellanemia. Individuals with sickle cell anemia and carriers of the sickle cell allele have someresistance to malaria. Malaria is caused by the parasite Plasmodium and is transmitted among humans by mosquitoes. If scientists are successful in reducing significantly or eliminating malaria, the best predictionfor what will happen to the allele for sickle cell anemia in the population is that it willa. not be affected by the elimination of malariab. increase as its selective advantage is increasedc. be reduced as its selective advantage is decreasedd. disappear quickly as its selective advantage is increasedarrow_forward
- Humans who are born homozygous for the recessive sickle cell allele die of sickle cell anemia, while those who are heterozygous are resistant to malaria. 5% of the population of the Congo are homozygous recessive for the sickle cell allele. What percentage of the population is resistant to malaria?arrow_forwardPolydactyly is an autosomal dominant trait that results in the presence of additional digits on the hands and feet. The incidence in Caucasians is approximately 1 in every 1300 births while in Africans and African Americans, the prevalence is 1 in every ~150 births. Fortunately, this trait does not cause any deleterious effects on one's health. Actually, there are a number of individuals who have been successful football players that were born with polydactyly. In 1902, a study found that the allele frequency of the recessive allele (p) was 30% in the local population. Last year, a follow-up study was published which assessed the genotypes of the same local population. The following data were obtained: pp = 10%; Pp = 40%; PP = 50% Use the above information to answer the questions below. Use the word bank for a subquestion when provided. What is the frequency of p (recessive allele) in the follow-up study? Round your answer to the nearest tenth. Did the population evolve?…arrow_forwardAbout 9 percent of Caucasian males are color-blind andcannot distinguish red-colored from green-coloredobjects.a. Offer one genetic model for color blindness.b. Explain why and how color blindness has reached afrequency of 9 percent in this populationarrow_forward
- Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a condition that there are not enough healthy red blood cells to carry oxygen throughout the body due to the production of red blood cells that are sickle shaped. The frequency of the sickle cell condition is as high as 10% in Central Africa compared to 0.5% in the United States. Calculate the frequency of the normal and carries of the sickle cell condition.arrow_forwardWhy is the color blindness gene still common in today's population?arrow_forwardThe following pedigree of the Tonks family follows the recessive inheritance on the MC1R gene for Metamorphmagus (the ability to change physical appearance). What are the possible genotypes for the following wizards for the MC1R gene? I: 1 Ted Tonks = ______________ I: 2 Andromeda Black = _________________ II: 2 Remus Lupin = _______________ III:1 Teddy Tonks = _______________arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education