Evolutionary Analysis (5th Edition)
5th Edition
ISBN: 9780321616678
Author: Jon C. Herron, Scott Freeman
Publisher: PEARSON
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Textbook Question
Chapter 1, Problem 12Q
Not all viruses are dangerous. (The common cold is an example.) HIV, however, is nearly 100% lethal. Describe three major hypotheses for why HIV is so highly lethal.
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In details, compare the life cycles of influenza virus and measles virus (4-5 points of contrasting).
Thank you!
The Ro of Ebola has been estimated to be somewhere between 1.5 and 2. See graphic below.
The number of people that one sick person will infect (on average) is called R₂.
Here are the maximum R, values for a few viruses.
more contagious
R₂-
Hepatitis C (2) Ebola (2)
HIV (4)
SARS (4)
Mumps (10)
Measles (18)
****
What percentage of the population would have to be vaccinated to stop the spread of Ebola if it were
to be introduced to a new continent?
a. 33-50%
O b. >99%
C. 75-99%
d. 66-75%
e. <33%
Rhinoviruses, the most common cause of colds, do not have a lipid envelope. Compared to enveloped viruses, these and other nonenveloped viruses tend to remain infectious outside the body longer, are more likely to be spread by contact with surfaces, and are less likely to be rendered harmless by exposure to hand sanitizer or hand washing. Explain how the lack of an envelope could contribute to these characteristics.
Chapter 1 Solutions
Evolutionary Analysis (5th Edition)
Ch. 1 - Prob. 1QCh. 1 - Prob. 2QCh. 1 - Prob. 3QCh. 1 - Given the risk of evolution of resistance, why do...Ch. 1 - Prob. 5QCh. 1 - Prob. 6QCh. 1 - In a monograph published in 1883, Alexander Graham...Ch. 1 - Design a study to test our prediction that human...Ch. 1 - Prob. 9QCh. 1 - Suppose that HIV were the ancestor of the SIVs,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Discuss the following statement: “Viruses exist in the twilight zone of life: outside cells they are simply dead assemblies of molecules; inside cells, however, they are alive.”arrow_forwardHPV viruses have a distinct capability to evade confrontation with the human immune system? What are the basic virus properties responsible for this capability? (Give at least 3)arrow_forwardEfforts to produce an HIV vaccine have met with limited success. What aspects of the virus and its replicative strategy make it difficult to produce a vaccine against HIV? What other kind of virus might be similarly different to vaccinate against? What similarities and differences exist between the two types of virus that account for the differences in vaccine production?arrow_forward
- An outbreak of Ebola between 2014 and 2016 resulted in 28,616 cases and 11,310 deaths in Guinea, Liberia and Sierra Leone. An additional 36 cases and 15 deaths were reported outside these 3 countries. This deadly disease urged the need for extensive research on Ebola to better understand and treat the disease and prevent future outbreaks. Ebola is a - SSRNA virus. What does this mean for how it is converted into proteins? Does this virus require additional machinery to be infectious? Can you hypothesize based on how it replicates in the cell what scientists might hope to target for treatment or prevention of Ebola?arrow_forwardModerna and Pfizer vaccines for COVID-19 use mRNA to the Spike protein combined with lipids. Which of the following is/are advantages of this type of vaccine compared to an inactivated virus vaccine? Select ALL correct answers. a) The vaccine is more stable for transport. b) The vaccine does not contain the virus so it cannot give you COVID-19. c) The vaccine can be rapidly produced in a slightly different form to protect from variants of SARS-CoV-2. d) The vaccine does not need a booster.arrow_forwardSeveral vaccines against viral infections are made by isolating purified surface proteins of the viral particle, mixing them with an adjuvant to stimulate an innate immune response, and injecting the mixture into people. Two examples of this are the vaccine against Hepatitis B virus, and the vaccine against Human Papilloma Virus (the ‘cervical cancer’ vaccine). One interesting property of vaccines of this type (known as ‘subunit vaccines’) is that there is a requirement for a CD4 T cell response to the vaccine antigen in order to generate antibodies to the innocuous protein in the vaccine. In the case of the Hepatitis B vaccine, the viral protein included in the vaccine is the Hepatitis B surface antigen (HepB-SAg), a protein that is approximately 200 amino acids in length. The graph in Figure Q4.27 shows the data from immunizing individuals with this vaccine, and monitoring their production of protective antibody responses to the viral protein. a) What results would be predicted if…arrow_forward
- What properties make HIV an "emerging virus"? HIV is now starting to cause diseases other than AIDS, such as rare types of cancers and pneumonias. HIV mutates rapidly, making the virus very different from HIV in the early 1980s. HIV infected humans long before the 1980s, but it has now mutated to a deadlier form. HIV suddenly became apparent and widespread in the 1980s.arrow_forwardThis is a hypothetical scenario. A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!arrow_forward1. Precise words:Find the nonspecific terms in the following sentences. Replace the nonspecific choices with more preciseterms or phrases (It is not necessary to change the sentence structure).(i) All OVE mutants showed enhanced iP concentrations.(ii) Plants were kept in the cold overnight.(iii) To provide proof of concept for our hypothesis, we studied a virus in its host cell.(iv) The present paper reports on continuing experiments that were performed to clarify thissurprising effect.(v) The first transition state is a little lower in energy than the second transition state. 2. Simple words:Improve the word choice in the following examples by replacing the underlined terms or phrases withsimpler word choices (do not change the sentence structure).(i) These data substantiate our hypothesis.(ii) The difference in our results compared to those of Reuter et al. (1995) can be accounted forby the fact that different conditions were used.(iii) For the purpose of discussing cell migration we…arrow_forward
- Rhinovirus, the most common cause of colds, do not have a lipid envelope. Compared to enveloped viruses these and other nonenveloped viruses tend to remain infectious outside the body longer, are more likely to be spread by contact with surfaces, and are likely to be rendered harmless by exposure to hand sanitizer or hand washing. Explain how the lack of an envelope could contribute to these characteristics.arrow_forwardAnswer the following and inlcude the references SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? Do you think that ART combinations/options might help in suppressing the viral replication of SARS-CoV-2? Expound.arrow_forwardAnswer the following 1.Are viruses living or non-living organisms? 2. What is the difference between HIV and AIDS? 3. HIV is classified as a retrovirus. What are retroviruses? 4. In your own words, provide a short summary of the HIV replication cycle. 5. Why is reverse transcriptase an important enzyme in the replication cycle of HIV? 6. In the chapter about enzymes, we have discussed how drugs are basically inhibitors. There are currently a multitude of Antiretroviral therapy (ART or ARV) options available to people living with HIV (PLHIV) so that the viral replication is suppressed and does not progress to AIDS. What do you think these drugs target? Discuss briefly. 7. SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? 8. In your own opinion, do…arrow_forward
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