Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 2, Problem 6P

The weak acid HA is 2% ionized (dissociated) in a 0.20 M solution.
a. What is Ka for this acid?
b. What is the pH of this solution?

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Consider the following pH titration curve of a diprotic acid.  What is the approximate values for pka 1 and pka 2? the curve is attached below.
The ionization of p-nitrophenol is shown below (pKa = 7.0): a. Identify the weak acid and conjugate base. b. At pH 7, what are the relative concentrations of ionized and un-ionized p-nitrophenol? c. If enough concentrated hydrochloric acid is added to a solution of p-nitrophenol to lower the pH from 7 to 5, what will happen to the relative concentrations of the ionized and un-ionized forms? d. Ionized p-nitrophenol has a yellow color, while the un-ionized form is colorless.  The yellow color can be measured using a spectrophotometer at 400nm.  In order to determine the total amount of p-nitrophenol in a solution, would you perform the spectrophotometer reading at an acidic or basic pH?  Clearly explain why? e. A solution of p-nitrophenol at pH 7.95 was found to have an A400 of 0.255 .  What is the total concentration (in µM) of p-nitrophenol (ionized plus un-ionized) in the solution?  The molar extinction coefficient of p-nitrophenol is 18,500 M-1cm-1 and the pKa is 7.
What is the pH of a 0.25 M solution of acetic acid, Ka = 1.8 x 105. What percentage of the acid is dissociated?
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GCSE Chemistry - Acids and Bases #34; Author: Cognito;https://www.youtube.com/watch?v=vt8fB3MFzLk;License: Standard youtube license