Biphenyl was used instead of benzene for this lab (Friedel-Crafts Alkylation) . What would be the predictable major product if benzene was used instead?
Q: In Synthesis of Diben zalacetone, why does the reaction end up being fully conjugated at the…
A:
Q: Show the reagents and the coupling partner that must be used in the above synthetic scheme.
A:
Q: Without changing reagent concentrations or amounts, what change could one make to the reaction shown…
A: Given reaction is Nucleophilic substitution reaction of 1o (primary) alkyl bromide , which is more…
Q: Show the two (neutral) organic starting materials that would be used to synthesize the compound…
A:
Q: Show the two (neutral) organic starting materials that would be used to synthesize the compound…
A: Note : Robinson annulation : Michael addition followed by intramolecular aldol condensation.
Q: In the grignard reaction, preparation of triphenylcarbinol summarize entire experiment in detail.
A: ph-C(ph)(OH)-ph : triphenylcarbinol ph-MgBr : Grignard reagent
Q: Give a possible resonance structure that could stabilise the negatively charged intermediary product…
A: Resonance structures can be defined as the Lewis structures which give information about the…
Q: We used biphenyl instead of benzene for Friedel-Crafts alkylation. What would you predict the major…
A: A Friedel-Crafts reaction is an organic coupling reaction involving an electrophilic aromatic…
Q: Why is methanol chosen as the solvent for recrystallization? What would happen if the student uses…
A: Dear student Many organic compounds are dissolved in alcohol and methanol is used as solvent in…
Q: Which reagent, cinnamic acid or cinnamoyl chloride is more reactive in the ester synthesis? Give…
A:
Q: Write down the aldol condensation between two acetaldehyde molecules. Determine the nucleophile,…
A:
Q: Lewis Acid
A: Ans. When we reacts m-xylene with tert-butyl chloride (Friedal-crafts alkylation ),there are…
Q: For the reaction shown, draw the transient product of one equivalent of reagent adding across the…
A: The given alkyne is converted into alkene (product A) in presence of 1 mol of H2,Pt
Q: Show how enols, enolate ions, andenamines act as nucleophiles
A:
Q: The following compound can't be synthesized using the methods discussed in this chapter. Why not?
A: Introduction Why the compound shown (m nitrotoluene) cannot be prepared using the methods studied in…
Q: Mixed aldol condensations involving benzaldehyde yield typically a single prodact Draw the structure…
A:
Q: What is the product of the below reaction?
A: This is a reaction where the alkynes are getting reduced to trans alkenes in the presence of Na,…
Q: Cross-aldol reactions are a convenient route to synthesizing B-hydroxyketones and aß- unsaturated…
A:
Q: Show the arrow pushing mechanism for getting tropylium ion from the benzylic carbocation
A: In the given question we have to rearrange the benzylic carbocation to tropylium ion.
Q: What product is likely to be isolated if a two-fold excess of acetone were added during this…
A: Acetone is a simple and colourless ketone. It is chemically propanone. The compound is highly…
Q: Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone…
A: Given: product
Q: Would you expect acetate ion CH3CO2 to be a better nucleophile in an SN2 reaction with an alkyl…
A: The SN2/E2 reaction of alkyl halide is with neutral nucleophile/base, the increasing polarity of the…
Q: Draw the benzoic acid structure and explain which products will be formed as a result of the…
A: Benzoic acid is an aromatic compound (carboxyl group attached to benzene ring) and aromatic…
Q: In a mixed aldol condensation with unknown aldehydes and ketones experiment, some aldol condensation…
A: An aldol reaction is a carbon-carbon bond formation reaction. The product formed by the aldol…
Q: how do i know if my aldol condensation is E or Z with the help of IR and NMR? what peaks should i be…
A:
Q: Please clearly draw the overall reaction taking place between methyl salicylate and sodium…
A:
Q: Would you expect methoxide ion to be a better nucleophile if it is dissolved in CH3OH or if it is…
A: Aprotic solvent are polar solvent molecules which do not have hydrogen bonded to oxygen to nitrogen.…
Q: to
A: This synthesis involves Michael addition, Aldol condensation, dehydration, hydrolysis and…
Q: In this experiment we will perform a Grignard addition to an ester. First we will form the Grignard…
A: Grignard reagent plays a vital role in organic chemistry.It has the tendency to form carbon-carbon…
Q: Examine
A: We will write the required information
Q: The reaction of an alkyl chloride with potassium iodide is generally carried out in acetone to…
A: Since potassium iodide is soluble in water while potassium chloride is not, the alkyl chloride will…
Q: Which is the correct order of reactivity for the following alkyl bromides in an El reaction?
A: Given : structure of alkyl halide. Reactivity of alkyl halide is directly proportional to the…
Q: One possible side-reaction of this experiment is biphenyl, explain how it can be formed. Here is…
A: The reaction given is, => bromobenzene →Magnesium Ph-MgBr+
Q: From each pair, select the stronger nucleophile. Q.)Cl2 or I2 in methanol
A: Given: Cl- and I- in methanol.
Q: This experiment is about synthesis of 1,3-diphenyl-2-propenone.Before the enone formation, how is…
A:
Q: What is the best way to remeber the differences between Sn1, Sn2, E1 and E2 reations?
A: The best way to remember differences between SN1, SN2, E1 and E2 reaction is that
Q: In this E1 reaction, why is it wrong to have include the alcohol and methyl group on the secondary…
A: The reaction in which substituents are removed is known as elimination reaction. The reaction occurs…
Q: Friedel-Crafts acylation
A:
Q: FRIEDEL-CRAFTS ALKYLATION The laboratory manual procedure was followed using the following…
A: In this question, we have to find out the correct answer of given problem by the help of the…
Q: what changes that you could make to the reducing benzil experimental procedure to improve the…
A: While reducing benzil to hydrobenzoin alcohol, NaBH4 must be used as a reducing agent (LiAlH4 should…
Q: What is the difference of using toluene, hexane, and dichloromethane as solvents in SN2 reactions?…
A:
Q: Give balanced overall reaction.
A: Important points. Friedal crafts alkylation is an electrophilic substitution reaction which…
Q: In the synthesis of methyl orange why do you add the reagents slowly and very precise. Why was this…
A: Methyl orange is an indicator , it shows different colors at different pH.
Q: During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important.…
A: The correct answer about Fridel crafts reaction is given below
Q: Based on the theoretical result in the table, what is the order of reactivity of primary, secondary,…
A: REACTIVITY OF ALKYL HALIDES WITH SODIUM IODIDE IN ACETONE
Q: What is a correct mechanistic step of this reaction?
A: The given reaction is SN2 reaction because the inversion of stereochemistry of reaction occurs .…
Q: How does the negative inductive effect (−I) of chlorine in the ortho position of the phenol, reduce…
A:
Biphenyl was used instead of benzene for this lab (Friedel-Crafts Alkylation) . What would be the predictable major product if benzene was used instead?
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
- During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important. Generally, these reactions are done by slowly adding the alkylating agent to the aromatic component. What is the advantage of mixing the ingredients in this order rather than slowly adding the aromatic component to the alkylating agent? + AICI3 + AICI3 add add slowly slowlyA common method where one alkyl halide is converted to another alkyl halide is known as Finkelstein reaction. In one example of this reaction the reaction of an alkyl chloride with potassium iodide is generally carry out in acetone to maximize the amount of alkyl iodine that this formed. Why does the solvent increase the amount of alkyl iodide. Hint: potassium idioide is soluble in acetone but potassium chloride is not.Explain why alkylation of an a-carbon works best if the alkyl halide used in the reaction is a primary alkyl halide, and why alkylation does not work at all if a tertiary alkyl halide is used.
- Why does the carbomethoxy group directs the reaction to positions that are meta to it ?b) Why the formation of dinitrobenzaote is substantially disfavored ?c) Would you expect small amounts of the ortho and para substituted product ? How would you remove them if they are formed ?d) Why does water have a retarding effect on the nitration ?e) Explain why Benzene has lower reactivity in electrophilic addition reactions than cyclohexene?Why does bromination give exclusively anti products while chlorination gives a mixture of syn and anti products?In EAS bromination reaction directly on aniline, there will be multiple products including ones in which two or more bromine atoms were incorporated onto the ring instead of only one. Why does this happen with aniline but not with acetanilide?
- Which of the included reagents is best for this reaction?This reaction is an example of conjugate addition of a nucleophile to an a,ẞ-unsaturated carbonyl. O CH3CH2CH2CH=CHCSCOA H₂O OH CH3CH2CH2CHCH2CSCOA Draw the two resonance structures of the enolate anion intermediate for this reaction. • Draw an R1 group in place of COA. The R group tool is located in the charges and lone pairs drop-down menu. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate resonance structures using the symbol from the drop-down menu. ->> 90-87 O + ? ChemDoodle >Draw the major product of the aldol addition reaction between two equivalents of this ketone with the conditions provided. Ignore inorganic byproducts. 1. H3O+ 2. Neutralizing work-up &