Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 9.5, Problem 1CC
Summary Introduction
To determine:
Whether the leading or lagging strand is made discontinuously in the direction opposite the movement of the replication fork.
Introduction
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Why can’t the lagging strand be synthesized in the same direction of the replication fork?
If deoxyribonucleotides that lack the 3’-OH groups are added during the replication process, what do you expect will occur?
What is the difference between the leading strand and the lagging strand in DNA replication?
There are different DNA polymerases involved in elongation of the leading strand and the lagging strand.
The leading strand is synthesized continuously in the 5' → 3' direction, while the lagging strand is synthesized discontinuously in the 5' → 3' direction.
The leading strand requires an RNA primer, whereas the lagging strand does not.
The leading strand is synthesized in the 3' → 5' direction in a discontinuous fashion, while the lagging strand is synthesized in the 5' → 3' direction in a continuous fashion.
Chapter 9 Solutions
Principles of Biology
Ch. 9.1 - Look ahead to Figure 17.10. How does bacterial...Ch. 9.1 - Prob. 1TYKCh. 9.2 - Prob. 1CCCh. 9.2 - Prob. 2CCCh. 9.2 - Prob. 3CCCh. 9.2 - A nucleotide composed of deoxyribose, phosphate,...Ch. 9.2 - Prob. 2TYKCh. 9.2 - Prob. 3TYKCh. 9.3 - Prob. 1TYKCh. 9.3 - To determine the structure of DNA, Watson and...
Ch. 9.4 - Prob. 1CCCh. 9.4 - Prob. 1TYKCh. 9.4 - Prob. 2TYKCh. 9.5 - Prob. 1CCCh. 9.5 - Prob. 1TYKCh. 9.5 - Prob. 2TYKCh. 9.5 - Prob. 3TYKCh. 9.6 - Prob. 1CCCh. 9.6 - A nucleosome is composed of 146 bp or 147 bp of...Ch. 9.6 - After they have replicated and become compacted in...Ch. 9.6 - Prob. 1BCCh. 9.6 - Which of the following is the correct order for...Ch. 9 - What is/are the main component(s) of chromosomes?...Ch. 9 - Prob. 2TYCh. 9 - Prob. 3TYCh. 9 - Prob. 4TYCh. 9 - Of the following statements, which is correct when...Ch. 9 - Prob. 6TYCh. 9 - Prob. 7TYCh. 9 - Prob. 8TYCh. 9 - Prob. 9TYCh. 9 - The conversion of euchromatin into heterochromatin...Ch. 9 - What are the four criteria that the genetic...Ch. 9 - What are the key features of DNA that allow it to...Ch. 9 - PRINCIPLES A principle of bioloy is that structure...Ch. 9 - Prob. 1CBQCh. 9 - Prob. 2CBQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The sequence below shows the ends of one strand of a linear chromosome, with slashes representing the middle part, which is not shown. During replication of this one strand, on which side of the slashes will Okazaki fragments be made in the newly synthesized strand? 5' AGCCGTACGGTTATCTCCTAG //// GGGCCTATTGTGACCAGTGAGTCG 3' a) Both sides b) Neither side c) The right side d) The left sidearrow_forwardDNA polymerase occasionally incorporates the wrong nucleotide during DNA replication. If left unrepaired, the base-pair mismatch that results will lead to mutation in the next replication. As part of a template strand, the incorporated wrong base will direct the incorporation of a base complementary to itself, so the bases on both strands of the DNA at that position will now be different from what they were before the mismatch event. The MER-minus strain of yeast does not have a functional mismatch excision repair system, but it has normal base excision repair and nucleotide excision repair systems. Which of the following statements is correct about differences in the mutation spectrum between MER-minus and wildtype yeast? More than one answer is correct. Options: More point mutations will arise in MER-minus yeast. Fewer point mutations will arise in MER-minus yeast as compared with wildtype. Of the total point mutations that…arrow_forwardWhether the statement "In a replication bubble, the same parental DNA strand serves as the template strand for leading strand synthesis in one replication fork and as the template for lagging-strand synthesis in the other fork" is true or false.arrow_forward
- In terms of the new DNA strands that are generated, what are the differences between replication and conventional polymerase chain reaction?arrow_forwardLagging strand: is synthesized discontinuously in the replication fork. direction toward the N terminal to the C terminal From the nitrogenous base to the phosphate group 5-> 3' 3'-> 5 direction toward the Leading strand: is synthesized continuously in the replication fork. N terminal to the C terminal From the nitrogenous base to the phosphate group 5-> 3' O 3'-> 5' How would the DNA sequence GCTATA be transcribed to MRNA? GCUAUA CGATAT CGAUAU O GCUTUT What bases would be found on the other strand of the DNA sequence GCTATA ? GCUAUA CGATAT CGAUAU GCUTUT O O O O O OO OOarrow_forwardDNA polymerases are processive, which means that they remain tightly associated with the template strand while moving rapidly and adding nucleotides to the growing daughter stand. Which piece of the replication machinery accounts for this characteristic? Helicase Sliding Clamp Single Stranded Binding Protein Primasearrow_forward
- What is the end replication problem?arrow_forwardWhat does DNA polymerase need in order to make contact with a replication origin?arrow_forward"In a replication bubble, the same parental DNA strand serves as the template strand for leading strand synthesis in one replication fork and as the template for lagging-strand synthesis in the other fork" is true or false.arrow_forward
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