The major products obtained by the reactions of benzoyl chloride with the given compounds are to be determined. Concept introduction: The reaction of acyl chloride with carboxylic acid in the presence of pyridine results in the formation of acid anhydrides. When acyl chloride reacts with alcohol and pyridine is used as a catalyst, it results in the formation of ester as the final product. The reaction of acyl chloride with amines and ammonia in the presence of sodium hydroxide results in the formation of amides. The reaction of acyl chloride with water results in the formation of carboxylic acid as the final product.

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Answer 1

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.4, Problem 4P

Interpretation Introduction

Interpretation:

The major products obtained by the reactions of benzoyl chloride with the given compounds are to be determined.

Concept introduction:

The reaction of acyl chloride with carboxylic acid in the presence of pyridine results in the formation of acid anhydrides.

When acyl chloride reacts with alcohol and pyridine is used as a catalyst, it results in the formation of ester as the final product.

The reaction of acyl chloride with amines and ammonia in the presence of sodium hydroxide results in the formation of amides.

The reaction of acyl chloride with water results in the formation of carboxylic acid as the final product.

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MeO 22.55 One potential synthesis of the anti-inflammatory and analgesic drug nabumetone is chloromethylation (Problem 22.48) of 2-methoxynaphthalene followed by an acetoacetic ester synthesis (Section 19.6). 5 3 6 CH₂O CI acetoacetic ester synthesis HC 7 MeO MeO 1 8 2-Methoxynaphthalene Nabumetone (a) Account for the regioselectivity of chloromethylation at carbon 6 rather than at carbon 5 or 7. (b) Show steps in the acetoacetic ester synthesis by which the synthesis of nabum- etone is completed.

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Soved Select the keyword or phrase that will best complete each sentence. Key terms: Compounds that contain a nitrogen atom bonded directly to a carbonyl carbon are called amides amines carboxyl groups The conjugate bases of a carboxylic acid are carboxylate anions Compounds that conatin an OR group directly bonded to the carbonyl carbon carboxylic acid are known as esters is the base hydrolysis of an ester. ethers Fischer esterification are salts of long-chain carboxylic acids. Micelles primary Hydrolysis of a secondary amide wil produce a amine. and a Saponification Soaps Primary RCONH. are compounds that have the general structure secondary

Answer 2

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.4, Problem 4P

Interpretation Introduction

Interpretation:

The major products obtained by the reactions of benzoyl chloride with the given compounds are to be determined.

Concept introduction:

The reaction of acyl chloride with carboxylic acid in the presence of pyridine results in the formation of acid anhydrides.

When acyl chloride reacts with alcohol and pyridine is used as a catalyst, it results in the formation of ester as the final product.

The reaction of acyl chloride with amines and ammonia in the presence of sodium hydroxide results in the formation of amides.

The reaction of acyl chloride with water results in the formation of carboxylic acid as the final product.

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.4, Problem 4P

Interpretation Introduction

Interpretation:

The major products obtained by the reactions of benzoyl chloride with the given compounds are to be determined.

Concept introduction:

The reaction of acyl chloride with carboxylic acid in the presence of pyridine results in the formation of acid anhydrides.

When acyl chloride reacts with alcohol and pyridine is used as a catalyst, it results in the formation of ester as the final product.

The reaction of acyl chloride with amines and ammonia in the presence of sodium hydroxide results in the formation of amides.

The reaction of acyl chloride with water results in the formation of carboxylic acid as the final product.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.4, Problem 4P

Interpretation Introduction