Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 18, Problem 3P
Effects of Changing Metabolite Concentrations on Glycolysis In an erythrocyte undergoing glycolysis what would be the effect of a sudden increase in the concentration of
a. AΤP?
b. AMP?
c. fructose-1.6-bisphosphate?
d. fructose-2, 6-bisphosphate?
e. citrate?
f. glucose-6-phospthate?
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Which of the statements below regarding glyphosate are true? (Choose all true statements)
A.Glyphosate interacts with EPSP synthase because it resembles the substrate S-3P
B.The interaction of S-3P is necessary for glyphosate binding.
C.Glyphosate likely binds to both conformations of EPSP synthase shown in question 7.
D.Glyphosate decreases Km for S-3P and thus likely the increases the affinity of the enzyme for substrate
E.Glyphosate likely increases feedback inhibition by the product of the reaction EPSP
Upon the addition of diazonium salts, ketoacids like glutamate and pyruvate forms in the presence of hydroxide as a color developer in Reitman Frankel Method. At pH 6.8, Pyruvate kinase catalyzes the transfer of phosphate from phosphoenolpyruvate to ADP to become ATP
a. both false
b. both are true
c.. only second is true
d. only first is true
2. constriction of the sphincter of oddi may cause falsely ______ in ____ activity
a. none of the choices
b. decresed, lipase
c. increased, ck-mb
d. increaased, amylase
e. decreased, LDH
3. The amyloclastic method of amylase activity determination refers to the measurement of the disappearance of the starch substrate when mixed with amylase in the sample. The addition of L-tartrate measurement of CP activity increases the sensitivuty of the substrate used to the prostatic ACP isoenzyme
a. both are true
b. both are false
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d. only first is true
A point mutation in Hb diminishes hydrophobicity at the heme. Which of the following impacts would you predict?
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Increased oxidation of Fe2+ and loss of O2 binding
b.
Decreased negative charges needed at the dimer/dimer interface to stabilize the T-state
c.
Decreased positive charges needed at the dimer/dimer interface to stabilize the T-state
d.
Shift the O2 binding curve of Hb to the left
e.
Decreased affinity for BPG in the T-state
Chapter 18 Solutions
Biochemistry
Ch. 18 - Characterizing Glycolysis List the reactions of...Ch. 18 - Radiotracer Labeling of Pyruvate from Glucose...Ch. 18 - Effects of Changing Metabolite Concentrations on...Ch. 18 - Prob. 4PCh. 18 - Prob. 5PCh. 18 - The Reactions and Meehanisms of the Leloir Pathway...Ch. 18 - The Effect of lodoacetic Acid on the...Ch. 18 - Prob. 8PCh. 18 - Comparing Glycolysis Entry Points for Sucrose...Ch. 18 - Prob. 10P
Ch. 18 - Prob. 11PCh. 18 - Prob. 12PCh. 18 - Prob. 13PCh. 18 - Energetic of Fructose-1 ,6-bis P Hydrolysis...Ch. 18 - Prob. 15PCh. 18 - Energetics of the Hexokinase Reaction The...Ch. 18 - Prob. 17PCh. 18 - Distinguishing the Mechanisms of Class I and Class...Ch. 18 - Prob. 19PCh. 18 - Understanding the Mechanism of Hemolytic Anemia...Ch. 18 - Prob. 21PCh. 18 - Based on your residing of this chapter, what would...Ch. 18 - Examine the ActiveModel for alcohol dehydrogenase...Ch. 18 - Based on your knowledge of the structure of NAD+...Ch. 18 - Using the ActiveModel for phosphofructokinase...
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