Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 10.5, Problem 1R
Summary Introduction
To review:
The way in which the common intermediates link the pathways of glycolysis, citric acid cycle, and photosynthesis.
Introduction:
All the
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What are the substrates and products of the net reaction corresponding to one turn of the citric acid cycle?
What is the citric acid cycle? Provide a schematic diagram of the citric acid cycle with chemical structures of each compound in the cycle. Indicate the cofactors and products at each step as well as the name of each of the enzymes involved.
What is the net reaction of the citric acid cycle? What happens to each product?
OXIDATIVE PHOSPHORYLATION:
3A) Thoroughly explain the biological significance of NADH/H* and FADH₂ and their roles in
oxidative phosphorylation.
3B) Describe and diagram the general pathway of the electrons from NADH/H+ and FADH2 to 02
during the electron transport chain.
3C) What is "chemiosmotic coupling", and what is its relationship to ATP synthesis?
3D) During oxidative phosphorylation, what is oxidized and what is phosphorylated?
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Life: The Science of Biology
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- How is succinate dehydrogenase unique compared with the other enzymes in the citric acid cycle?arrow_forwardWhat is the significance of substrate-level phosphorylation reactions? Which of the reactions in the citric acid cycle involve a substrate-level phosphorylation? Name another example from a biochemical pathway with which you are familiar.arrow_forwardName the molecules that conserve most of the energy from the redox reactions of the citric acid cycle (see Figure 9.12). How is this energy converted to a form that can be used to make ATP?arrow_forward
- What steps of the citric acid cycle are regulated? How and why are they regulated?arrow_forwardWhat steps in the citric acid cycle are regulated? Why arethey regulated?arrow_forwardWhat three molecules produced during the citric acid cycle are an indirect or direct source of high-energy compounds?arrow_forward
- What molecules areproduced as a result of the citric acid cycle?arrow_forwardWhat enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH? What enzymes from the citric acid cycle that allosterically regulated by NAD+?arrow_forward(a) Convert the ball-and-stick model of B, one of the eight synthetic intermediates in the citric acid cycle, to a structural formula, and name the compound. (b) What is the immediate precursor of B in the citric acid cycle; that is, what compound forms B as a reaction product? (c) What compound is formed from B in the citric acid cycle?arrow_forward
- What citric acid cycle enzyme is also a component of the electron-transport chain?arrow_forwardWhat reaction serves to link glycolysis and the citric acid cycle, and what is the enzyme that catalyzes the reaction?arrow_forwardHow many turns of the citric acid cycle are implicated in accounting for the net oxidation of one (1) mole of fructose to carbon dioxide and water?arrow_forward
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