Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 23RQ
A gene that codes for a positive cell-cycle regulator is called a(n).______
- kinase inhibitor
- tumor suppressor gene
- proto-oncogene
- oncogene.
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Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- Determine if the gene on the left is a proto-oncogene or tumor suppressor. APC p53 Ras [Choose] [Choose] Tumor suppressor Proto-oncogene [Choose]arrow_forwardThe genes for retinoblastoma (pRB) and p53, act as ________ in regulating the cell cycle. oncogenes proto-oncogenes pseudo-oncogenes tumor enhancer genes tumor suppressor genesarrow_forwardA normally functioning gene that regulates the cell cycle by stopping cell division is most likely to be a(n) __________. Group of answer choices carcino-gene tumor suppressor proto-oncogene muta-gene oncogenearrow_forward
- Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.arrow_forward"In the cellular regulatory pathways that control cell growth and proliferation, the products of oncogenes are stimulatory components and the products of tumor suppressor genes are inhibitory components" is true or false.arrow_forwardAnswer each question with a paragraph; 3-5 sentences each. Explain the difference between a proto-oncogene and a tumor-suppressor gene. Explain the difference between prokaryotic and eukaryotic cell division. Explain the difference between positive regulation of the cell cycle and negative regulation of the cell cycle. Explain the difference between normal p53 and mutated p53. Find two differences and two similarities between binary fission and mitosis.arrow_forward
- Relatively few inherited forms of cancer involve the inheritance of mutant oncogenes. Instead, most inherited forms of cancer are defects in tumor-suppressor genes. Give two or more reasons why inherited forms of cancer seldom involve activated oncogenes.arrow_forwardCancer is a genetic disease. To provide evidence that you understand cancer genes are altered in both sporadic (somatic) and inherited cancers, match the beginning and end of the sentences below to give correct statements. NOTE: there is one extra, redundant answer, do not use it. This question has partial credit, so you will still be awarded some marks even if all of your sentences are not correct. Prompts Gain of function Oncogenes Mutated forms of proto-oncogenes Examples of oncogenes Loss of function. Examples of tumor suppressor genes Tumor suppressor genes Inherited cancer The Knudson's 2-hit hypothesis Both inherited and sporadic cancers Submitted Answers Choose a match Choose a match Choose a match Choose a match. Choose a match. Choose a match Choose a match. Choose a match. Choose a match Choose a match. ▼ ▼ ▼ O protect cells from uncontrolled proliferation are; CMYC, KRAS & ErBb2 is seen in oncogenes, leading to cancer. involve Tumor suppressor genes are not involved in…arrow_forwardYou are looking at the results of a western blot from the lysates of cells harvested from a suspected breast cancer tumor and you see that there is an increased expression of INK4-p16, you suspect that this will______________? Group of answer choices Increase S to G2 phase transition Initiate a cell cycle arrest in G1 Block M to G1 phase transition Promote tumorigenesisarrow_forward
- The normal copies of tumor-suppressor genes encode proteins that have which three types of interrelated functionsarrow_forward_____________ stem cells are capable of differentiating into nearly all cell types, while _________________ stem cells can only differentiate into a limited number of cell types.arrow_forwardO Tumors of the blood A tumor with limited growth Explain why radiation and 5-fluorouracil are effective cancer treatments. Please include a few sentences about how these treatments interact with the cell cycle. Your answer Any comments please use this space (e.g. to clarify an answer or point o issues on questions, etc.)arrow_forward
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