Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 19RQ
Which protein is a positive regulator that phosphorylates other proteins when activated?
- p53
- retinoblastoma protein (Rb)
- cyclin
- cyclin-dependent kinase (Cdk)
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The epidermal growth factor receptor (EGFR) activates a complex signaling network
to increase expression of several genes and promote cell proliferation as shown in
the figure below.
EGF
Active EGFR
Inactive EGFR
Inactive EGFR
P-
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NUCLEUS
МЕК-F
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Which of the following scenarios would result in decreased expression of the c-myc
gene?
Select all that apply
A homozygous mutation of the EGFR gene resulting in a deletion of the ligand
binding domain
A homozygous mutation of the ras gene so that Ras protein was not able to
exchange GDP for GTP
A homozygous mutation of the ras gene so that Ras protein was not able to
hydrolyze GTP for GDP
A homozygous mutation of the MAPK gene so that MAPK protein was always in
a phosphorylated state
Which of the following is false about cyclin-cdk complexes?
OCdk's do not have to bind to cyclin proteins for complex to be active.
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Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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