True or False: The presence of Howell-Jolly bodies on a blood smear is indicative of asplenia or functional hyposplenism.
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- In your own words, discuss the common problems associated with routine blood smear preparation during capillary punctureAnswer the question(s) in reference to the five disorders listed below: Hutchtinson-Gilford progeria hemophilia turner syndrome down syndrome klinefelter syndromeA 12-weeks pregnant woman complains of inability to focus, fatigue, and shortness of breath. On a physical examination, she looks pale and weak. Laboratory results are as follows: Reticulocyte count: 1%, Hematocrit: 27%; Hemoglobin: 6.5 g/dL; MCV: 105 fL, MCHC: 32%. If the patient's transfusion reactions history suggests anaphylactic reactions, which blood component should be given? Justify your answer.
- A healthy 28-year -old female sees her physician for a routine examination and blood work: Total bilirubin 2.8 mg/dL Direct bilirubin 0.1 mg/dL Indirect bilirubin 2.7 mg/dL These resulta correlate with which of the following conditions? 1) Normal, healthy individual 2) Biliary obstruction 3) Dubin-Johnson sundrome 4) Gilbert's disease no references, just homeworkMatch the descriptor in the left hand column to the type of molecule it describes listed in the right hand column.. Question 4 options: hemoglobin molecule with heme groups containing iron atoms in the reduced state to which carbon monoxide molecules are attached hemoglobin molecule with heme groups containing iron atoms in the reduced state to which oxygen molecules are attached hemoglobin molecule with heme groups containing iron atoms in the oxidized state to which no oxygen molecules can attach hemoglobin molecule with heme groups containing iron atoms in the reduced state to which no oxygen molecules are attached hemoglobin molecule with heme groups containing iron atoms in the reduced state and carbon dioxide molecules attached to amino acid residues of the globin chains 1. carbaminohemoglobin 2. carboxyhemoglobin 3. deoxyhemoglobin 4. methemoglobin 5. oxyhemoblobinIn Ingested poisoning and carbon monoxide poisoning, how would a person know she/he has thia disease/disorder? How does a doctor diagnose this disease/disorder?)(X-ray, MRI, blood test, other laboratory test)
- What is hairy cell leukaemia? ( in details) -mention the diagnosis through bone marrow biopsy and through morphology of cells ( WBC, RBC, PLT, HCT, HGB and MCV)BACKGROUND A 2-year-old black girl is being seen by the hematologist after her pediatrician found her to be severely anemic with splenomegaly and jaundice. Her mother gives a possible history of a “blood problem” in her family but doesn’t know for sure. Her hemoglobin electrophoresis was normal, and the complete blood count (CBC) revealed a normocytic anemia. The platelet and white blood cell counts are normal. On the peripheral smear, there are many bizarre erythrocytes, including spiculated cells. A diagnosis of pyruvate kinase deficiency is made. Pyruvate kinase deficiency (PKD) can be inherited in an autosomal recessive manner, which means that a child must inherit a gene with the disease-causing mutation from both parents in order for the disorder to be inherited. The PLKR gene regulates the synthesis of the pyruvate kinase enzyme, which is located in the liver and red blood cells. Pyruvate kinase deficiency (PKD) is a rare genetic disorder characterized by the premature…Background introduction about blood smear
- Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. What other history data would be helpful in determining the cause of this disorder?Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. Which of MB’s clinical signs are reflective of the body’s effort to compensate for the decreased oxygen carrying capacity seen with this condition?Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. What type of hematologic disorder would you suspect based on MB’s laboratory values? Why?
