In order to metabolize ethanol, the liver uses a pathway that involves alcohol dehydrogenase and aldehyde dehydrogenase. Both of these enzymes generate NADH,NADH, which then

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter17: Anti-infective Drugs
Section: Chapter Questions
Problem 20CRQ
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In order to metabolize ethanol, the liver uses a pathway that involves alcohol dehydrogenase and aldehyde dehydrogenase. Both of these enzymes generate NADH,NADH, which then accumulates, contributing to the development of fatty liver disease.

SELECT ALL of the processes that describe the effects of NADHNADH accumulation?

a.promotion of triacylglycerol hydrolysis

b.promotion of fatty acid synthesis

c.inactivation of transcription factor

d.changes in gene transcription

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