How do polar protic and aprotic solvents affect the reactivity of enolates ? 2.

Q: what is the roll of sodiumacetate in Beckamann rearrangement ?

A:

Q: Draw the keto tautomer of attached enol.

A: The keto tautomer of attached enol can be drawn as

Q: Draw the structure of synthetic intermediate B. F но SOCI2 A B Pyridine

A:

Q: Which is a reasonable intermediate in an aldol reaction of propanal? HO

A: Aldol reaction is a type of condensation reaction in which carbonyl compound having alpha H atom…

Q: What carbonyl starting materials are needed to prepare each compound using a directed aldol…

A: a.

Q: (a) Draw two different halo ketones that can form A by an intramolecular alkylation reaction. (b)…

A: Given compound,

Q: Draw the products formed in each crossed aldol reaction.

A: The cross-aldol reaction takes place between 2 different carbonyl compounds. That is, they occur…

Q: Rank the following according to increasing reactivity with 1 as the least reactive, and 4 as the…

A: The reactivity order for nucleophilic acyl substitution is as follows:

Q: Draw the reactivity series for nucleophilic substitution at the carbonyl carbon. (You may exclude…

A: Reactivity series for nucleophilic substitution at the carbonyl carbon?

Q: How to draw any nucleophilic substitution product ?

A:

Q: Draw the nucleophilic attack of the thiamine ylide on a molecule of benzaldehyde. Use proper…

A:

Q: What two molecules were condensed in an aldol reaction to form the compound below? H. and and H. and…

A:

Q: 5.45 Use resonance structures of the possible carbocation intermediates to explain why bromination…

A:

Q: Rank each of the enolates from least to most stabilized with 1 being the least and four being the…

A: The ions given are,

Q: A)There are two plausible enolates that can arise when LDA is used as the base for the ketone shown.…

A: LDA stands for lithium diisopropyl amide , its molecular formula is [(CH3)2CH]2NLi.  LDA is used…

Q: O A successful Claisen condensation requires an ester starting material with at least one alpha…

A: Ketone alpha hydrogen is slightly acidic in nature. This is due to the stabilization of the…

Q: Draw the mechanism for nitration of phenylacetic acid. Include formation of the electrophile. The…

A: Given reaction,       Nitration of phenylacetic acid

Q: (disconnect to a "diketone" (a) (b) (c) starting material)

A:

Q: Explain why compound A does not undergo an E2 elimination with strong base.

A: For the structure to be more stable it has to have the bulky phenyl group in the equtorial position.…

Q: (a) Draw two different halo ketones that can form A by an intramolecularalkylation reaction. (b) How…

A: (a)

Q: 7. Related question a. Draw all theoretically possible aldol condensation products for the following…

A: Please find below all the possible products of the reaction

Q: What are the General Features of the Aldol Reaction ?

A: Aldol reactions: These are the organic reactions in which there is the formation of a new bond…

Q: Which ester, C or D, is more reactive in nucleophilic acyl substitution?Explain your reasoning.

A:

Q: Draw the mechanism for thr reaction of an aldehyde or a ketone with hydride iron.

A: The carbonyl compounds undergo nucleophilic addition-elimination reaction.

Q: What starting materials are needed to synthesize each attached compound by a Robinson annulation?

A: Robinson Annulation is an organic reaction that takes place between alpha-beta unsaturated carbonyl…

Q: What ring-closing metathesis product is formed when each substrate is treated with Grubbs catalyst…

A: The catalyst which is used for the olefin methasis is Grubb's catalyst. The Grubb's catalyst is…

Q: enolate I and aldehyde Il shown below. OLi A) electrophile = I; nucleophile = || B) nucleophile = I;…

A: Those species which donate its lone pair or electron density called nucleophiles and those species…

Q: LDA is the base of choice for carbonyl compound to completely convert into enolate. Why?

A: The full form of LDA is Lithium diisopropylamide. It has isopropyl groups create hindrance and make…

Q: Why is the nitro group a meta director? Select one: O a. Because it adds electron density to the…

A: 1. Nitro is electron withdrawing group. It will remove electron density from o, p positions.…

Q: a) Which structure is more reactive toward electrophilic aromatic substitution (EAS reaction) ? b)…

A: a)Reactivity In electrophilic aromatic substitution Electron withdrawing groups or electron…

Q: In step 7, a hydroperoxide ion reacts with the glycosulose molecule to form a peroxy intermediate.…

A: The functional groups are key components associated with a molecule and are highly responsible for…

Q: Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol…

A: The enolate nucleophile ion in its carbanion form and Carbonyl electrophile.This is intramolecular…

Q: 4. Provide a retrosynthesis only. Ph Ph Ph Ph

A: Retrosynthesis of the following compounds is given below.

Q: Rank the follo Mucieophilic acyl subst and number 3 in the dio) om im -N Explain why 1 is mor

A: Amides can be defined as the organic compounds that contain CONH2 group

Q: 5.2 (a) Draw the Intermediate product resulting from the arrow movement in compound A. (b) Circle…

A:

Q: which

A: We will write the mechanism

Q: What is Crossed aldol reactions ?

A: Aldol reactions between two different carbonyl compounds are known as crossed aldol reactions.

Q: 1. Why is aldol product the major product in relation to the Cannizzaro reaction?

A: Note: Since you have posted a question with multiple subparts, we will solve the first three…

Q: Could you explain the main characteristics and occurences in nucleophilic acyl substitution? Thank…

A: Nucleophilic acyl substitution describe a class of substitution reaction involving nucleophiles and…

Q: Explain why aprotic conditions favor a kinetic enolate ?

A:

Q: What is the major enolate (or carbanion) formed when each compound istreated with LDA?

A: (e) The major product of enolate (or carbanion) formed compound is treated with LDA is given below:

Q: CH3 ннн H H エエ

A: Α-hydrogen of carbonyl compounds are acidic in nature and it is removed in the presence of a base to…

Q: Which is a reasonable intermediate in an aldol reaction of propanal?

A: In aldol condensation two carbonyl molecules condensed to form betahydroxyaldehyde or…