CI CI ticlopidine

Q: What alkyl halide and nucleophile are needed to prepare each compound?

A: a. The cyanide ion (CN-) acts as a nucleophile on reaction with alkyl halide.  The reaction between…

Q: Br n +

A:

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: SOLUTION: Step 1: Pitavastatin (Livalo) is a lipid-lowering agent. It is used in the treatment of…

Q: One step in the synthesis of sitaglipitin (Problem 17.14, a drug used to treat type 2 diabetes)…

A:

Q: When trichloride J is treated with CH3OH, nucleophilic substitution forms the dihalide K. Draw a…

A: The given compound J contains three Cl groups at different position. The Cl group that is present…

Q: What is the structure of the product formed when A is heated in the presence of maleic acid? Explain…

A: The reaction in which cycloaddition reaction takes place is known as Diels-Alder reaction. The…

Q: What alkyl halides are needed to prepare each ketone using the acetoacetic ester synthesis?

A: Since you have posted a question with multiple questions, we will solve first question for you. To…

Q: What product is formed when a solution of A and B is treated with mild base? This reaction is the…

A: Diseases, such as high-risk vascular disease and abnormal lipids are treated with the help of…

Q: Rank the compounds in each group in order of increasing reactivity toward nucleophilic attack.

A: a) Aldehydes are more reactive than ketones towards Nucleophilic attack. This is because, due to…

Q: Draw the product when each compound is treated with either (CH3)2CuLi, followed by H2O, or HC≡CLi,…

A: a. figure 3

Q: Draw a stepwise mechanism for the following reaction. Draw the transition state for each step.

A: Concept introduction: Alkene molecules generally shows addition reaction due to the presence of…

Q: What product is formed when a solution of A to B is treated with mild base? This reaction is the…

A: The first step is the abstraction of an acidic proton by base from structure B as shown below : This…

Q: What is the major enolate (or carbanion) formed when each compound istreated with LDA?

A:

Q: Draw the products formed from nitration of each compound.

A: (a) Nitration product of p-cresol is, OH group is powerful ortho para directing group than Me so…

Q: 9.49 Draw a stepwise mechanism for the following reaction. Он H,SO. H20

A: Major Product:- Major product will be 1-methylcyclopentene. Because there are 3 substituents on this…

Q: What neutral nucleophile is needed to convert dihalide A to ticlopidine, an antiplatelet drug used…

A: The structure of ticlopidine is different from the structure of dihalide A. One of the chlorine…

Q: What acetylide anion and epoxide are needed to synthesize each compound?

A: (a) From the retro synthesis, Acetylide anion and epoxide are needed to synthesize the given…

Q: CPC (cetylpyridinium chloride), an antiseptic found in throat lozenges and mouthwash, is synthesized…

A: The reaction of pyridine with alkyl halide results in the electrophilic addition reaction at the N…

Q: susceptible to nucleophilic attack a to b c only a only a and c

A:

Q: What carbonyl compound and CBS reagent are needed to prepare X, an intermediate in the synthesis of…

A: These are the following Aldehyde and CBS reagent involved in the reaction where the attack of the…

Q: Determine which ring in each compound is more reactive in electrophilic aromatic substitution, and…

A:

Q: Draw a stepwise mechanism for the intramolecular Friedel–Crafts acylation of compound A to form B. B…

A: Concept introduction: The Friedel-Craft acylation is a type of electrophilic substitution reaction.…

Q: Identify A in the following reaction scheme, and draw a stepwise mechanism for the conversion of A…

A:

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: Protonation of oxygen atom takes place in the presence of acid H3O+ Hydrogen atom migrates to…

Q: What enolate is formed when each ketone is treated with LDA in THF solution? What enolate is formed…

A: LDA is a strong non nucleophilic base and it abstracts proton from alpha position of less hindered…

Q: Even though B contains three ester groups, a single Dieckmann product results when B is treated with…

A:

Q: Draw the product and stepwise mechanism for the following reaction. HCI Low Temperature

A:

Q: Draw a stepwise mechanism for the following intramolecular reaction, which is used in the synthesis…

A: The given compound is the female sex hormone Estrone.

Q: What is the major enolate (or carbanion) formed when each compound is treated with LDA?

A: The major product of enolate (carbanion) formed when the compound is treated with LDA is given…

Q: What neutral nucleophile is needed to convert dihalide A to ticlopidine, an antiplatelet drug used…

A: The ticlopidine is framed by supplanting one of the Cl with a nucleophile.  Also, the nucleophile…

Q: Which N atom in each compound is more basic? What product is formed when each compound is treated…

A: Comparing to amides, amine is more basic since the electron pair present on nitrogen atom is highly…

Q: Draw a stepwise mechanism for the following reaction, which results in the synthesis of bisphenol F…

A: A stepwise mechanism for the given reaction can be shown below

Q: What neutral nucleophile is needed to convert C to D? Imatinib, an effective treatment for certain…

A: Since in C and D, the difference is of and Cl part  hence it means has attacked on the molecule and…

Q: Draw a stepwise mechanism for the following reaction, which involves both a Diels–Alder reaction and…

A: [4+2]-cycloaddition of a conjugated diene and a dienophile (an alkene or alkyne), an electrocyclic…

Q: What starting materials are needed to synthesize each compound using a Robinson annulation?

A: Part A

Q: Although γ-butyrolactone (Problem 19.62) is a biologically inactive compound, it is converted in the…

A: First, involves protonation of given compound. Then carbonyl groups gets converted into -OH group on…

Q: Q2/ What is the major E2 elimination product formed from each halide? CH H. CH 3. b. CH CH, CH,CH,…

A: (a) In an E2 reaction, both H and Br groups must be in anti periplanar to each other (i.e. 180…

Q: Draw a stepwise mechanism for the following reaction, which results in the synthesis of bisphenol F…

A: The organic reactions help in the synthesis of various new organic compounds.

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A:

Q: Rank the following compounds in order of increasing reactivity in nucleophilic addition.

A: Given compounds,

Q: a. CHO b.

A: Intermolecular aldol reaction leads to the formation of unsaturated carbonyl compound. In…

Q: What is the major enolate formed in each reaction?

A: For useful alkylation reactions of enolate anions, in the absence of other strong nucleophiles and…

Q: Q#6 Draw a stepwise mechanism for the following reactions. a) (b) HO. H2SO4 hex-5-en-1-ol

A:

Q: Draw the products formed when A or B is treated with fo following agent. In some cases, no reaction…

A: Grignard reagent is an organo-magnesium reagent which is generally prepared by treating an alkyl…

Q: What carbonyl compound and CBS reagent are needed to prepare X, an intermediate in the synthesis of…

A: The CBS reagent is used for the asymmetric reduction of the carbonyl compound to the corresponding…

Q: 45. The indicated bond is: A) Nucleophilic because it is electron-deficient. B) Electrophilic…

A: Since you have posted multiple questions, we are entitled to answer the first only. 45) The compound…

Q: Draw the keto tautomer of each enol.

A: Tautomers are isomers of a compound which differ only in the position of the protons and electrons.

Q: Captopril is a drug used to treat high blood pressure and congestiveheart failure. What product is…

A: Captopril is a drug used to treat high blood pressure and congestive heart failure.

Q: (a) Draw a stepwise mechanism for the conversion of A to B. (b) What product would be formed if C…

A: LDA is used as s strong base which abstracts H+ from the more acidic position. This generates an…

Aldehydes and Ketones

Aldehydes and ketones are organic compounds that have a carbonyl group, C = O, as their functional group. They both differ in the placement of this carbonyl group in their structures.