G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are two basic receptor types by which cells transduce signals. Classify each statement as describing GPCRs, RTKs, both types of receptors, or neither. GPCRs structure contains seven transmembrane helices activate heterotrimeric G proteins directly ligand binding induces conformational change in receptor an example is the epinephrine receptor RTKs receptor activation causes phosphorylation of its cytosolic subunits an example is the insulin receptor autophosphorylation of receptor can initiate signal Both phosphorylation of receptor can terminate signal or desensitize receptor Neither transports some ligands through the membrane

G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are two basic receptor types by which cells transduce signals. Classify each statement as describing GPCRs, RTKs, both types of receptors, or neither. GPCRs structure contains seven transmembrane helices activate heterotrimeric G proteins directly ligand binding induces conformational change in receptor an example is the epinephrine receptor RTKs receptor activation causes phosphorylation of its cytosolic subunits an example is the insulin receptor autophosphorylation of receptor can initiate signal Both phosphorylation of receptor can terminate signal or desensitize receptor Neither transports some ligands through the membrane

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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