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- This is remdesivir, one of the drugs being used in the treatment of COVID-19. Label the indicated carbons as R, S, or neither. b); NH2 HO OHDefine the following: 1. Cofactor 2. Coenzyme 3. "-ase" endingAn amino acid mixture consisting of lysine, leucine, and glutamic acid is to be separated by ion-exchange chromatography, using a cationexchange resin at pH 3.5, with the eluting buffer at the same pH. Which of these amino acids will be eluted from the column first? Will any other treatment be needed to elute one of these amino acids from the column?
- One of the main sources of sphingosine in the body is in the cell membrane. What complication could arise from the biological synthesis of ceramide?In ion-exchange chromatography, amino acids are separated on the basis of electro-static interactions and hydrophobic interactions with the resin. The chemical structure of the resin pol-ymer with a negatively charged sulfonic acid group is shown to the right. An elution profile for the aminoacids using this resin is given below. Based on the elution profile above, explain the following:A prescription calls for 4 mg of atropine on a balance where 180 mg is the least weighable quantity with the precision desired. What amount will provide the 4 mg correctly, using lactose as the diluent?
- Using DEAE-cellulose as ion exhange resin, indicate the starting and ending pH for the narrowest experimental pH range used to seperate an amino acid mixture consisting of Ala, Cys and His Starting pH: Ending pH:An amino acid mixture consisting of lysine,leucine, and glutamic acid is to be separated by ion-exchangechromatography, using a cation-exchange resin at pH 3.5, with theeluting buffer at the same pH. Which of these amino acids will beeluted from the column first? Will any other treatment be neededto elute one of these amino acids from the column?Based on this video https://www.youtube.com/watch?v=rKng5-ij6kQ Provide a schematic diagram for the Iodine test methodologies in determining the presence of carbohydrates. Also, give the basic principle for the test.
- Cyanogen bromide is a common sulfhydryl-modifying reagent that can generally be used to break disulfide bonds. True FalseFatty acids are isolated using a surface embedded with silver ions. The composition of a fatty acid mixture was identified,and the shorthand notations of the fatty acid and triglyceride names were identified.Sample A – 18:0Sample B – trans-18:1∆9Sample C – cis, cis-20:2∆9, ∆12Sample D – 1,2-dibutyroyl-3-caproyl glycerolSample E – 1,2-dioleoyl-3-linoleoyl glycerolSample F – phosphatidylcholineWhich among these fatty acids and triglycerides, respectively, will MOST LIKELY be isolated by the described surface?Illustrate the condensed and skeletal structures of your answer(s). Provide a ten-sentence explanation to justify youranswers using relevant chemistry concepts.Identify the biomolecule represented by the following image. O=P-O. 5' Base ОН 4" 1' 3 2' ОН