A 60-year-old man presents with headaches and pruritis. Physical examination reveals splenomegaly but no lymphadenopathy. A CBC demonstrates elevated hemoglobin of 19.5 g/dL, WBC of 12,800/uL, and platelets of 550,000/mL. The bone marrow displays hypercellularity of all lineages and depletion of marrow iron stores. Which of the following is the most likely diagnosis?
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A 60-year-old man presents with headaches and pruritis. Physical examination reveals splenomegaly but no lymphadenopathy. A CBC demonstrates elevated hemoglobin of 19.5 g/dL, WBC of 12,800/uL, and platelets of 550,000/mL. The bone marrow displays hypercellularity of all lineages and depletion of marrow iron stores. Which of the following is the most likely diagnosis?
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