BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 9.5, Problem 1LO
Summary Introduction
To contrast: The signaling through GPCRs and RTKs.
Introduction: Receptors are the chemical structures that bind with the signal molecules called as a ligand. The ligand molecules can be proteins, peptides, and lipids that induce the signal transduction pathway with binding to the receptor molecules. For instance, the ligand acetylcholine binds to the acetylcholine receptor that induces the transmission of nerve impulse between the nerves.
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List two ways that GPCR signaling transduction can be turned off (go back to inactive state)
You are studying the role of CAMP in cell
signaling. You hypothesize that 2
intracellular signaling proteins, named GO
and TIGERS, interact with each other
when cells are treated with an extracellular
source of CAMP. The two proteins were
tagged with CFP or YFP (CFP = cyan
fluorescent protein; YFP = yellow
fluorescent protein). CFP is excited by 435
nm light and emits lights at 480 nm. YFP
is excited by 480 nm light and emits light
at 535 nm.
400
500
Wavelength of
Emitted Light
400
500
Wavelength of
Emitted Light
600
600
Fluorescence
400
400
500
Wavelength of
Emitted Light
600
500
Wavelength of
Emitted Light
600
Fluorescence
Intensity
400
500
Wavelength of
Emitted Light
600
Figure Legend. A. Cells expressing GO-CFP
irradiate with 435 nm light. B. Cells
expressing TIGERS-YFP and irradiated with
435 nm light. C. Cells expressing TIGERS-
YFP and irradiated with 480 nm light. D.
Cells expressing GO-CFP and TIGERS-YFP
and irradiated with 435 nm light. E. Cells
expressing GO-CFP and…
Illustrate a complete cell signaling cascade from signal to response. Each protein in the pathways must be shown. You can choose either a GPCR or an RTK mediated pathway.
Chapter 9 Solutions
BIOLOGY
Ch. 9.1 - Prob. 1LOCh. 9.1 - Prob. 2LOCh. 9.2 - Prob. 1LOCh. 9.3 - Prob. 1LOCh. 9.3 - Prob. 2LOCh. 9.4 - Prob. 1LOCh. 9.4 - Describe how information crosses the membrane in...Ch. 9.4 - Prob. 3LOCh. 9.4 - Prob. 4LOCh. 9.5 - Prob. 1LO
Ch. 9.5 - Prob. 2LOCh. 9 - Paracrine signaling is characterized by ligands...Ch. 9 - Signal transduction pathways a. are necessary for...Ch. 9 - The function of a ____is to add phosphates to...Ch. 9 - Which of the following receptor types is NOT a...Ch. 9 - How does the function of an intracellular receptor...Ch. 9 - Signaling through receptor tyrosine kinases often...Ch. 9 - Prob. 7UCh. 9 - Which of the following best describes the...Ch. 9 - Prob. 1ACh. 9 - The ion Ca2+ can act as a second messenger because...Ch. 9 - Different receptors can have the same effect on a...Ch. 9 - In comparing small G proteins like Ras and GPCR...Ch. 9 - Prob. 5ACh. 9 - The receptors for steroid hormones and peptide...Ch. 9 - Describe the common features found in all examples...Ch. 9 - The sheet of cells that form the gut epithelium...
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