Life: The Science of Biology
Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
bartleby

Videos

Question
Book Icon
Chapter 7.2, Problem 1R
Summary Introduction

To review:

The dissociation constant (KD) and the information conveyed by it about the production of a cellular response.

Introduction:

Dissociation constant refers to the quantity that is expressing the extent to which a certain substance present in the solution is the broken into ions. It is equal to the product of the concentrations of the individual ions divided by the total concentration of the undissociated molecule.

Blurred answer
Students have asked these similar questions
A ligand binds two different receptors with a Kd value of 10−7 M for receptor 1 and a Kd value of 10−9 M for receptor 2. For which receptor does the ligand show the greater affinity? Calculate the fraction of receptors that have a bound ligand ([RL]/RT) in the case of receptor 1 and receptor 2 if the con- centration of free ligand is 10−8 M.
After establishing the importance of cGMP in the signaling pathway of the photoreceptor cells, the researchers wish to identify the exact target of cGMP. The researchers suspect that cGMP binds to an ion channel, causing the observed change in the membrane potential between the dark and the light conditions but they are not sure which one. The researchers determine the movement of three different ions (sodium, chloride and potassium) as a function of their respective electrochemical gradient across the plasma membrane: ● Sodium tends to enter the cell Chloride tends to enter the cell Potassium tends to leave the cell The researchers therefore propose three simple hypotheses for the effect of cGMP on the membrane potential of the rod photoreceptor cell: ● Hypothesis A: CGMP binds to a sodium-channel, that opens and lets sodium ions diffuse inside the cell. Hypothesis B: cGMP binds to a chloride-channel, that opens and lets loride ions diffuse inside the cell. Hypothesis C: cGMP binds to…
CYP2E1 has a much higher Km for ethanol than ADH (11 mM versus 0.05 mM,respectively). When greater portions of ethanol are ingested (0.08% or 17 mM), which part of the statement would be true?
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Phlebotomy: Venipuncture Procedure; Author: Medical Lab Lady Gill;https://www.youtube.com/watch?v=LC9LABPts7M;License: Standard Youtube License