Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
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Chapter 26.6, Problem AQ
Interpretation Introduction
Interpretation:
Among the given statements, one challenge to understand the carboxylation of glutamate side chain in biological setting has to be identified.
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Which of the following is a challenge to understanding how the carboxylation of glutamate side chains is feasible in a biological setting?
1. Because the pKa of the a-hydrogen of glutamate is 27, it is too high to be effectively deprotonated at physiological pH.
2. The C-C bond formed in a 1,3-dicarboxylate is too weak to exist in a biological setting.
3. b-Dicarboxylic acids spontaneously decarboxylate at neutral pH.
4. Both 1 and 3.
From which amino acid are serotonin and melatonin synthesized? What types of reac-
tions are involved in their biosynthesis?
HO,
CH,CH,NH,
CH,O,
CH,CH,NHCCH,
(a)
(b)
H
Serotonin
Melatonin
Dipalmitoylphosphatidylcholine is a surfactant found in the lining of the lungs. It prevents the lungs from collapsing when the lung volume is low and protects the lungs from injuries caused by inhaled particles. Draw its structure.
Chapter 26 Solutions
Organic Chemistry
Ch. 26.1 - Prob. 26.1PCh. 26.6 - Prob. AQCh. 26.6 - Prob. BQCh. 26.6 - Prob. CQCh. 26.6 - Prob. DQCh. 26.6 - Prob. FQCh. 26 - Prob. 26.2PCh. 26 - Identify the hydrophobic and hydrophilic region(s)...Ch. 26 - Prob. 26.4PCh. 26 - Prob. 26.5P
Ch. 26 - Prob. 26.6PCh. 26 - Prob. 26.7PCh. 26 - Prob. 26.8PCh. 26 - Prob. 26.9PCh. 26 - How many moles of H2 are used in the catalytic...Ch. 26 - Prob. 26.11PCh. 26 - Prob. 26.12PCh. 26 - Prob. 26.13PCh. 26 - Prob. 26.14PCh. 26 - Prob. 26.15PCh. 26 - Prob. 26.16PCh. 26 - Prob. 26.17PCh. 26 - Prob. 26.18PCh. 26 - Prob. 26.20PCh. 26 - Prob. 26.21PCh. 26 - Prob. 26.22PCh. 26 - Prob. 26.23PCh. 26 - Following is a structural formula for cortisol...Ch. 26 - Prob. 26.25PCh. 26 - Draw the structural formula of a lecithin...Ch. 26 - Prob. 26.27PCh. 26 - Prob. 26.28PCh. 26 - Prob. 26.29PCh. 26 - Prob. 26.30PCh. 26 - Prob. 26.31PCh. 26 - Prob. 26.32PCh. 26 - Prob. 26.33P
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