Biology Today and Tomorrow without Physiology (MindTap Course List)
Biology Today and Tomorrow without Physiology (MindTap Course List)
5th Edition
ISBN: 9781305117396
Author: Cecie Starr, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 2, Problem 3DID

Effects of Dietary Fats on Lipoprotein Levels

Cholesterol that is made by the liver or that enters the body from food does not dissolve in blood, so it is carried through the bloodstream by lipoproteins. Low-density lipoprotein (LDL) carries cholesterol to body tissues such as artery walls, where it can form deposits associated with cardiovascular disease. Thus, LDL is often called “bad” cholesterol. Highdensity lipoprotein (HDL) carries cholesterol away from tissues to the liver for disposal, so HDL is often called “good” cholesterol. In 1990, Ronald Mensink and Martijn Katan published a study that tested the effects of different dietary fats on blood lipoprotein levels. Their results are shown in Figure 2.23.

Chapter 2, Problem 3DID, Effects of Dietary Fats on Lipoprotein Levels Cholesterol that is made by the liver or that enters

Figure 2.23 Effect of diet on lipoprotein levels.

Researchers placed 59 men and women on a diet in which 10 percent of their daily energy intake consisted of cis fatty acids, trans fatty acids, or saturated fats. Blood LDL and HDL levels were measured after three weeks on the diet; averaged results are shown in mg/dL (milligrams per deciliter of blood). All subjects were tested on each of the diets. The ratio of LDL to HDL is also shown.

Source, Mensink RP, Katan MB, “Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects.” NEJM 323(7):439–45.

An elevated risk of heart disease has been correlated with increasing LDL-to-HDL ratios. Rank the three diets according to their predicted effect on cardiovascular health.

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Transport of lipids in blood involve lipoproteins which includes the LDL and HDL commonly referred to as the “good and bad cholesterol” respectively.  True  False
Cholesterol that is made by the liver or that enters the body from food does not dissolve in blood, so it is carried through the bloodstream by lipoproteins. Low-density lipoprotein (LDL) carries cholesterol to body tissues such as artery walls, where it can form deposits associated with cardiovascular disease. Thus, LDL is often called "bad" cholesterol. High-density lipoprotein (HDL) carries cholesterol away from tissues to the liver for disposal, so HDL is often called "good" cholesterol.   LDL levels were highest in the diet containing primarily ______.   A. cis fatty acids   B. saturated fats   C. trans fatty acids
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