Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Question
Chapter 17.3, Problem 1CC
Summary Introduction
To determine: Whether a genetic disease caused by a mutant allele, in whichboth the affected parents produce an unaffected offspring, can have a recessive nature.
Introduction: Genetic disorders are caused due to abnormalities in the genome of a person and these disorders are inheritable from the parents to the offspring. Genetic disorders can be autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y linked or mitochondrial disorders. In order to understand inheritence of human genetic diseases “Pedigree analysis” is considered the most efficient tool and it follows simple Mendelian pattern.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Using the link provided. Mate two flies. a male is a wild type and a female has yellow body and purple eyes.
Use: https://www.sciencecourseware.org/FlyLabJS/
Which mutant alleles are dominant? Which mutant alleles are recessive?
Which mutant alleles are sex-linked? Which mutant alleles are autosomal?
Can you tell at this point if the two genes are linked?
Show the results of the dihybrid analysis. Are genes segregating independently? What is the evidence for or against this?
Show the crosses you will use to obtain the mapping data.
For the mapping crosses, Write out the crossing scheme and make a table of the results (ignore sex in this table, combine the male and female progeny). Identify the parental classes and the recombinant classes. For a 3-point cross, identify the double cross overs. Show your calculations for the recombination frequencies between the three genes (for the 3-point cross) or the two genes (for the two-point crosses).
Draw a map of…
In genetics, what does a genotype of Hh signify?
Choose 1 answer:
Choose 1 answer:
(Choice A)
A
Homozygous; two dominant alleles
(Choice B)
B
Homozygous; two recessive alleles
(Choice C)
C
Heterozygous; one dominant allele and one recessive allele
(Choice D)
D
Homozygous; one dominant allele and one recessive allele
Mutant female: yellow body and purple eyes.
Male: Normal
Use: https://www.sciencecourseware.org/FlyLabJS/
Which mutant alleles are dominant? Which mutant alleles are recessive?
Which mutant alleles are sex-linked? Which mutant alleles are autosomal?
Can you tell at this point if the two genes are linked?
Show the results of the dihybrid analysis. Are genes segregating independently? What is the evidence for or against this?
Show the crosses you will use to obtain the mapping data.
For the mapping crosses, Write out the crossing scheme and make a table of the results (ignore sex in this table, combine the male and female progeny). Identify the parental classes and the recombinant classes. For a 3-point cross, identify the double cross overs. Show your calculations for the recombination frequencies between the three genes (for the 3-point cross) or the two genes (for the two-point crosses).
Draw a map of the Drosophila chromosomes 2, 3, and X, including…
Chapter 17 Solutions
Biology
Ch. 17.1 - Prob. 1CCCh. 17.1 - Prob. 2CCCh. 17.1 - Prob. 3CCCh. 17.1 - Prob. 4CCCh. 17.1 - Mendels Laws of Inheritance Concept Check: What...Ch. 17.2 - Prob. 1CSCh. 17.2 - Prob. 2CSCh. 17.2 - Prob. 1CCCh. 17.3 - Prob. 1CCCh. 17.3 - Prob. 2CC
Ch. 17.4 - Prob. 1CCCh. 17.4 - Prob. 1EQCh. 17.4 - Prob. 2EQCh. 17.4 - Prob. 3EQCh. 17.5 - Prob. 1CSCh. 17.5 - Prob. 1CCCh. 17.6 - Prob. 1CCCh. 17 - Prob. 1TYCh. 17 - During which phase of nuclear division does the...Ch. 17 - Prob. 3TYCh. 17 - Which of Mendels laws cannot be observed in a...Ch. 17 - During a __________blank, an individual with the...Ch. 17 - Prob. 6TYCh. 17 - Prob. 7TYCh. 17 - A hypothetical flowering plant species produces...Ch. 17 - Genes located on a sex chromosome are said to be...Ch. 17 - Prob. 10TYCh. 17 - Prob. 1CQCh. 17 - A cross is made between individuals having the...Ch. 17 - Core Concept: Systems We can view life as a...Ch. 17 - Discuss the principles of the chromosome theory of...Ch. 17 - When examining a human pedigree, what patterns do...
Knowledge Booster
Similar questions
- Part 1: Make a three part process drawing (like a cartoon strip) to demonstrate Mendel's Principle of Segregation. Use two parents with homologous chromosomes marked with alleles "A" and "a". Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes (indicate when this happens), and c) gametes from each parent combine at random to form diploid offspring Part 2: Use the cross Aa x Aa and a Punnett square to demonstrate Mendel's Principle of Segregation. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes and c) gametes from each parent combine at random to form diploid offspring. Part 3: Use homologous chromosomes marked with alleles "A" and "a" and a second pair of homologs marked with alleles "B" and "b". to demonstrate Mendel's Principle of Independent Assortment in cells in Meiosis. Indicate what phase this…arrow_forwardPart 1: Make a three part process drawing (like a cartoon strip) to demonstrate Mendel’s Principle of Segregation. Use two parents with homologous chromosomes marked with alleles “A” and “a”. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes (indicate when this happens), and c) gametes from each parent combine at random to form diploid offspring Part 2: Use the cross Aa x Aa and a Punnett square to demonstrate Mendel’s Principle of Segregation. Circle and label these three action parts of the Principle of Segregation: a) parents are diploid, b) alleles separate to form haploid gametes and c) gametes from each parent combine at random to form diploid offspring. Write the expected genotypic and phenotypic ratios.arrow_forwardQUANTITATIVE Recall that hemophilia is an X-linked recessive disease. If a woman with hemophilia had children with a man without hemophilia, what is the chance that their first child will have the disease? What is the chance that their first child will be a carrier?arrow_forward
- Explain why most loss-of-function alleles are recessive to wild-type, but some are incompletely dominant or (rarely) dominant?arrow_forwardRecessive epistasis: In a cross between fruit flies that are both double heterozygous for modifier gene and coat color, in the total offspring of 192, how many fruit flies have gray- coat, white coat, and black coat? A recessive allele blocks the expression of the coat color of fruit flies. Show your answer and solution.arrow_forwardExplain why most loss-of-function alleles (hypomorphic or amorphic) are recessive to wild-type alleles, but some are incompletely dominant or dominant.arrow_forward
- Suppose a mutant fruit fly with blue eyes was recently discovered. It is later determined that the blue eye trait is recessive to the wild-type red eye trait. What is the most common way to represent the mutant and wild-type alleles?. Choices are Mutant: Bl, bl Wild-type: Bl+ , re, bl+, or wtarrow_forwardName: Class Date Polygenic Inheritance: Cat Coat Color Read aboutthe inheritance of cat coat color In each cat below, predict the phenotype of each genotype and color in each catl Make sure you indicate whether each cat is male or female One gene that affects coat color in cats is an x linked gene we'll call the pigment gene. One allele causes black fur (X) and one allele gives the cat orange fur (X"). These alleles act in a codominant manner, because when a cat has two different alleles (XB Xb), the cat has a pattern called tortoise shell, where the cat has both orange and black hairs. The Y chromosome does not have this coat color gene There is another gene that affects coat color in cats called the piebalding gene. This gene is on an autosomal chromosome and the alleles affect the amount of white patches that appear in the cat's coat, Some cats (ss) have o white patches and their other colors are blended, not patchy. Some cats (SS or Ss) have white patches and their other colors are…arrow_forwardSuppose a maternal effect gene exists as a functional dominant allele and a nonfunctional recessive allele. A mother with the disorder produces all offspring without the disorder. Explain the genotype of the mother.arrow_forward
- Suppose you are testing the null hypothesis that the mode of inheritance for a particular disease in elegant cranes is sex-linked recessive. You employ the following crosses, where R is the wild-type allele, r is the disease allele, and Y is Y-chromosome allele (only in males): Parental cross (Affected male with unaffected (carrier) female): rY x Rr. F₁ cross (Unaffected male with affected female): RY x rr. Suppose you perform these crosses at two different research locations. You obtain the following counts in the F2 generation: Location 01 Male, Disease: 200 Male, Wild-type: 225 Female, Disease: 211 Female, Wild-type: 205, Location 02 Male, Disease: 320 Male, Wild-type: 325 Female, Disease: 354 Female, Wild-type: 310 Do you reject or not reject the null hypothesis that the mode of inheritance is sex-linked recessive at each location? The significance level is 0.01. (Hint: when applying the ChiSq goodness of fit test, if the expected value for a row is 0, remove that row and reduce…arrow_forwarda. Why males and females do not show equal chances of inheriting a trait? b. Is it possible to determine the genotypes of the parents based on the phenotypes of the offspring?arrow_forwardConsider a couple: a woman who is homozygous for a recessive mutation that causes X-linked colorblindness, and a man with full color vision (he does not carry a copy of the mutation). a) What is the probability that a son of this couple will be colorblind? b) What is the probability that a daughter of the couple will be colorblind?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education