Biochemistry
Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 17, Problem 1RE

RECALL Which reaction or reactions that we have met in this chapter require ATP? Which reaction or reactions produce ATP? List the enzymes that catalyze the reactions that require and that produce ATP.

Expert Solution & Answer
Check Mark
Interpretation Introduction

Interpretation:

The reactions that require and produce ATP are to be named and the list of enzymes that catalyze those reactions during the process of glycolysis is to be provided.

Concept introduction:

Glycolysis is a metabolic pathway that converts one molecule of glucose into two molecules of pyruvate.

Glycolysis is an anaerobic process that occurs in the absence of oxygen.

Glycolysis is the fundamental system of sugar metabolism in the body that contributes to the production of energy in the form of ATP molecules.

Answer to Problem 1RE

Solution: The first step of glycolysis, which is the phosphorylation of glucose to glucose-6-phosphate, is catalyzed by the enzyme hexokinase and the third step of glycolysis, that is, the phosphorylation of fructose-6-phosphate to give fructose-1,6-bisphosphate is catalyzed by the phosphofructokinase enzyme. These two steps in the process of glycolysis require ATP for the reaction to take place.

The step involving the phosphorylation of ADP to  ATP, where 1,3-bisphosphoglycerate is converted into 3-phosphoglycerate, is catalyzed by the enzyme phosphoglycerate kinase and the step involving the conversion of phosphophenol-pyruvate to pyruvate is catalyzed by the enzyme pyruvate kinase. These two steps in the process of glycolysis produce ATP.

Explanation of Solution

The phosphorylation of glucose to glucose-6-phosphate, that is, the first step of glycolysis, which is initiated by an enzyme called hexokinase, requires one molecule of ATP (Adenosine triphosphate), which act as a source for the phosphate group, released as ADP(Adenosine diphosphate). Also, the phosphorylation of fructose-6-phosphate to give fructose-1,6-bisphosphate requires one molecule ATP (Adenosine triphosphate), which acts as a source for the phosphate group, released as ADP(Adenosine diphosphate). Both the reactions result in the conversion of glucose into two molecules of glyceraldehyde-3-phosphate.

The step where 1,3-bisphosphoglycerate is converted to 3-phosphoglycerate as well as the step involving the conversion of phosphoenol-pyruvate to pyruvate involve the phosphorylation of ADP to  ATP. The transfer of a phosphate group each from 1,3-bisphosphoglycerate and phosphoenol-pyruvate to ADP occurs.

Conclusion

Glycolysis results in the production of two molecules of ATP, NADH and pyruvate.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Chapter 17 Solutions

Biochemistry

Ch. 17 - REFLECT AND APPLLY In what way is the observed...Ch. 17 - REFLECT AND APPLLY How does ATP act as an...Ch. 17 - RECALL At what point in glycolysis are all the...Ch. 17 - RECALL Which of the enzymes discussed in this...Ch. 17 - RECALL Define substrate-level phosphorylation and...Ch. 17 - Prob. 16RECh. 17 - RECALL Which molecules act as inhibitors of...Ch. 17 - RECALL Many NADH-linked dehydrogenases have...Ch. 17 - RECALL Several of the enzymes of glycolysis fall...Ch. 17 - Prob. 20RECh. 17 - REFLECT AND APPLLY Is the reaction of...Ch. 17 - Prob. 22RECh. 17 - Prob. 23RECh. 17 - Prob. 24RECh. 17 - Prob. 25RECh. 17 - Prob. 26RECh. 17 - Prob. 27RECh. 17 - Prob. 28RECh. 17 - RECALL If lactic acid is the buildup product of...Ch. 17 - Prob. 30RECh. 17 - Prob. 31RECh. 17 - Prob. 32RECh. 17 - REFLECT AND APPLLY What is unique about TPP that...Ch. 17 - BIOCHEMICAL CONNECTIONS Beriberi is a disease...Ch. 17 - REFLECT AND APPLLY Most hunters know that meat...Ch. 17 - REFLECT AND APPLLY What is the metabolic advantage...Ch. 17 - BIOCHEMICAL CONNECTIONS Cancer cells grow so...Ch. 17 - Prob. 38RECh. 17 - Prob. 39RECh. 17 - REFLECT AND APPLLY Show how the estimate of 33%...Ch. 17 - Prob. 41RECh. 17 - Prob. 42RECh. 17 - Prob. 43RECh. 17 - Prob. 44RECh. 17 - REFLECT AND APPLLY Show, by a series of equations,...Ch. 17 - REFLECT AND APPLLY What should be the net ATP...Ch. 17 - Prob. 47RECh. 17 - Prob. 48RECh. 17 - Prob. 49RECh. 17 - REFLECT AND APPLLY According to Table 17.1,...Ch. 17 - Prob. 51RECh. 17 - Prob. 52RECh. 17 - REFLECT AND APPLLY High levels of...Ch. 17 - Prob. 54RECh. 17 - Prob. 55RE
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
  • Text book image
    Biochemistry
    Biochemistry
    ISBN:9781305961135
    Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
    Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY