Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 14, Problem 8QP
DNA Profiles as Tools for Identification
STRs are:
- a. used for DNA profiles
- b. repeated sequences present in the human genome
- c. highly variable in copy number
- d. all of these
- e. none of these
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a. It is possible to perform DNA fingerprinting withSNPs instead of SSRs as DNA markers, but ingeneral you would need to examine more SNPmarkers than the 13 SSRs used in the CODIS database to be sure of a match. Explain why.b. DNA fingerprinting has been used to verify pedigrees of valuable animals such as show dogs, racinggreyhounds, and thoroughbred horses. However, thetechnology is much harder to apply in these casesthan it is in forensic applications for humans. In particular, many more DNA markers must be examinedin domesticated animals to establish the identity orclose familial relationship of two DNA samples.Why would you need to look at more polymorphicloci in these animals than you would in humans?
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Chapter 14 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 14.6 - Suppose you are arrested for a serious crime and a...Ch. 14.6 - Prob. 2EGCh. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Biopharming: Making Human Proteins in Animals...Ch. 14 - Prob. 2QPCh. 14 - Prob. 3QPCh. 14 - Genetically Modified Foods The creation of...Ch. 14 - Prob. 5QP
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The current state-of-the-art in forensic DNA profiling involves the PCR-amplification and analysis ofshort tandem repeats, STRs, in the human genome. This approach has many distinct advantages.Please list and explain three of those advantages.arrow_forwardThe detection of single nucleotide polymorphisms is possible with: O A. Restriction Enzymes O B. All the mentioned methods O C. Sanger sequencing O D. High Resolution Melting analysis O E. TaqMan probesarrow_forwardConsider the four extraction/purification methods . a. Which extraction method would you use for a touch DNA sample? Explain your reasoning.b. Which extraction method would you use for a sample containing a mixture of primarily non-human and some human DNA? INFO: the 4 extraction methods are QIAamp manual extraction, QIAcube semi-automated extraction, DNA IQ extraction, or FTA punch purificationarrow_forward
- Briefly explain the rationales of adding chemicals which can affect DNA stability in polymerase chain reaction (PCR).arrow_forwardYou have two sewage samples that you want to check for the SARS Cov 2 viral load. Whichvariable would give you a good estimate?a. High Ct valueb. Low Ct valuec. High melting temperatured. Low melting temperaturee. None of the above The DNA fragments generated during a cycle sequencing reaction are separated by sizes usingcapillary gel electrophoresis. The determination of the actual sequence is based on detection ofa. fluorescently labelled ddNTPsb. the lengths of the fragmentsc. fluorescently labelled probesd. fluorescently labelled primers.arrow_forwardGel electrophoresis can be used to separate DNA on the basis of: A. the probe used. B. size. C. G and C nucleotide content. D. both size and loading buffer content. E. loading buffer content.arrow_forward
- In primer designing, which of the following statements is correct? a. Primers should be 18-24 bases in length. b. Base composition should be 45-55% (G+C). c. Melting temperatures between 55-70°C are preferred. d. All choices are correct.arrow_forwarddescribe the principles and procedures used with CODIS for DNA -based identificationarrow_forwardMicroarray hybridization is used mostly in transcript profiling or assaying DNA variation. Although the technology for establishing DNA microarrays was developed only recently, numerous applications have already been developed and their impact on future biomedical research and diagnostic approaches is expected to be profound. Give some examples of the practical use of this technique.arrow_forward
- a. If you forgot to add dNTPs to a sequencing reaction, what would be the result? Only very long fragments would be synthesized Only very short fragments would be synthesized The fragments would not be labelled DNA polymerase would be inactivated Sequencing would proceed normally b. Please also answer the imagearrow_forwardChoose the one answer that fits best. Which of the following statements regarding DNA Fingerprinting is NOT correct (videos)? a. Fingerprinting is a technique that allows us to sequence an entire genome b. Forensic DNA profiling uses 13 different regions of DNA (according to the video) c. STRs allow us to tell individuals apart d. Short tandem repeats are in the non-coding regions e. DNA Fingerprinting is used in Forensic Sciencesarrow_forwardA genetic profile cana. assist an individual in maintaining good health.b. be accomplished utilizing bioinformatics.c. show how many genes are normal.d. be accomplished utilizing a microarray.e. Both a and d are correct.arrow_forward
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