Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 12.5, Problem 1R
Summary Introduction
To review:
The pattern of inheritance in case of Leber’s hereditary optic neuropathy disorder when the woman is affected but the man is not and when the man is affected but the woman is healthy.
Introduction:
The maternal inheritance pattern is observed in case of autonomous organelles carrying their own set of deoxyribonucleic acid (DNA). Maternal inheritance means that the genetic material in case of autonomous organelles is contributed by the female only.
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Hemophilia is a typical example of Sex-Linked Inheritance. If the man is hemophilic and marries a homozygous normal woman. What will be the genotype of the female child?
In humans, hemophilia is a sex-linked recessive disease, and the gene is located on the X chromosome. A man with hemophilia marries a woman with hemophilia. What is the probability of a daughter they have been a hemophiliac?
Hemophilia A, a condition in which blood does not clot properly, is a recessive trait located on the X chromosome (Xh). A woman heterozygous for the trait marries a normal male. What is the probability that this couple will have hemophiliac daughters? What is the probability that this couple will have hemophiliac sons?
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Life: The Science of Biology
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- a human disease known as cystic fibrosis is inherited as a recessive trait.Two unaffected individuals have a first child with the disease. What isthe probability that their next two children will not have the disease?arrow_forwardWilma and Wally have one male child who has been diagnosed withDuchenne muscular dystrophy, an X-linked condition that results insevere atrophy of skeletal muscle. Neither parent has this condition.What is the probability that their next child will have Duchenne musculardystrophy?arrow_forwardA human disease known as cystic fibrosis is inherited as a recessive trait. Two unaffected individuals have a child who has the disease. What is the probability that their next two children will NOT have the disease?arrow_forward
- In humans,curly hair is dominant over straight hair.A woman heterozygous for hair marries a man with straight hair.What is the probability that the first child will have curly hair?What is the probability that the second child will have curly hair?arrow_forwardA karyotype shows that a child has Klinefelter syndrome (47,XXY). If the child is also colorblind (due to a recessive X-linked allele), despite his parents having normal color vision, in which parent and stage of meiosis did nondisjunction occur? And explain why .arrow_forwardIs the probability of having offsprings that are identical twins hereditary?arrow_forward
- Male pattern baldness is a recessive sex-linked trait on the X chromosome (Xb). A woman, who is homozygous dominant for male pattern baldness marries a man Who has male pattern baldness. What is the probability that any son born will have pattern baldness?arrow_forwardMuscular dystrophy is a group of disorders that involve muscle m weakness and loss of muscle tissue that get worse overtime. A homozygous normal female has children with a male who has muscular dystrophy. What is the probability that they will have a child who is both MALE and HAS MUSCULAR DYSTROPHY?arrow_forwardHemophilia is a disease caused by a recessive allele (h), which is found on the X chromosome, non-hemophilia is (H). A normal man marries a woman that is heterozygous for the trait. Give the genotypes and phenotypes of all possible offspring?arrow_forward
- Hemophilia is a disease caused by a gene found on the X chromosome. Therefore, it is a sex-linked disease which is caused by the recessive allele. Suppose, a man with hemophilia marries a woman who is homozygous dominant for the trait. Predict the genotype of the man. (XH = normal; Xh= hemophiliac) * a. XH Y b. XHXh c. XhXh d. Xh Yarrow_forwardA woman with keratosis, a skin condition caused by a rare dominant allele, marries a man with normal skin. If they have a son, what is the probability that he will have normal skin?arrow_forwardHemophilia (reduced blood clotting) is an X-linked recessive disease in humans. A woman with hemophilia mates with a man who exhibits normal blood clotting. What is the probability that their child will have hemophilia?arrow_forward
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