Which of the following is/are true for sickle-cell anemia? I. It results from a point mutation on the beta sub-unit which results to the amino acid substitution of V with E. II. The sickle-shaped RBC's are vaso-occluded in the capillaries resulting to damage in various internal organs. TIt. Hemoglobin precipitates when deoxygenated, resulting to the distortion in the shape of the thrombocytes. Select the correct response: Il only I, ll, and Ill ll and III I only Ill only l and lI

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter11: The Blood
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10 Which of the following is/are true for sickle-cell anemia?

I. It results from a point mutation on the beta sub-unit which results to the amino acid substitution of V with E.

II. The sickle-shaped RBC's are vaso-occluded in the capillaries resulting to damage in various internal organs.

TIt. Hemoglobin precipitates when deoxygenated, resulting to the distortion in the shape of the thrombocytes.

Select the correct response:

  • Il only
  • I, ll, and Ill
  • ll and III
  • I only
  • Ill only
  • l and lI
  • land IlI
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