When the molecule reacting with the electrophile is a strong nucleophile and a strong base, the substitution reaction is favoured when There is the least amount of crowding (steric hindrance) around the alpha carbon There is the most amount of crowding (steric hindrance) around the alpha carbon The leaving group is a strong base
When the molecule reacting with the electrophile is a strong nucleophile and a strong base, the substitution reaction is favoured when There is the least amount of crowding (steric hindrance) around the alpha carbon There is the most amount of crowding (steric hindrance) around the alpha carbon The leaving group is a strong base
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
Problem 15E
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Transcribed Image Text:When the molecule reacting with the electrophile is a strong nucleophile and a
strong base, the substitution reaction is favoured when
There is the least amount of crowding (steric hindrance) around the alpha carbon
There is the most amount of crowding (steric hindrance) around the alpha carbon
The leaving group is a strong base
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