In order to complete the synthesis shown below, you would need to use [ Select ] as the nucleophile source and [ Select ] as the solvent. H3C OH H3C Br H3 H3C- CH3 CH3
Q: SCH3 OCH3 Br N(CH3)2 1 2 3 A) 3>1> 2>4 B) 3> 2>1>4 C) 4 > 2 > 3 >1 D) 1>3> 2 > 4
A: Order the carboxylic acid derivatives from most reactive to least reactive towards nucleophilic…
Q: Which bases can be used for an E2 reaction that follows Hofmann's rule? Choose all that apply. O…
A: According to Hoffman rule, an elimination reaction occurs to produce less substituted alkene which…
Q: Which do you think is a stronger nucleophile in an SN2 reaction-pyridine or pyrrole? Explain. H.…
A: The complete Lewis structures of the two compounds are
Q: Provide a multi-step synthesis to create the intended product for the listed original reactant. The…
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Q: B. In each of the following pairs, circle the species that is more reactive toward nucleophilic…
A: We know that greater electrophilicity of the carbonyl, then faster will be the nucleophilic attack
Q: BOH)2 Pd(PPH3)4 Br K2CO3
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Q: From each pair, select the stronger nucleophile. Q.) CH3OCH3 or CH3SCH3
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Q: What is the main product from the reaction sequence below?
A: First, let's discuss the given reaction. The initial reactant used in the reaction is styrene. The…
Q: Consider the following reaction below. Which of the following choices has the con sequences of…
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Q: Complete the synthesis of the target molecules below (on the left) from the starting material (on…
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Q: Indicate the reagent needed for the below reaction: н он
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Q: Rank the following compounds in order of increasing SN2 reaction rate with a good nucleophile.…
A: We have to rank the given compounds in order of increasing SN2 reaction rate with a good…
Q: Rank the following in terms of reactivity towards a nucleophile (1 = least reactive and 4 = most…
A: Electrophiles are reagents that are electron deficient. These attack reagents that are rich in…
Q: Alkyl diazonium salts (shown below) are considered "super" leaving groups; a consequence of this is…
A: Alkyl diazonium salts are the excellent leaving group because R- N2+ because nitrogen is an…
Q: synthesis. the letters of the reagents in the order that they are used; example: fa. Reagents…
A: Given : We have to write the reagent and prepare the given product from benzene.
Q: ?Which of the following is not a nucleophile اخترأحد الخیارات a. NH3 -b. Br c. FeBr3 d. CH30CH3
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Q: SH 5 steps
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Q: What is the appropriate electrophile nucleophile and solvent to achieve this final product
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Q: What nucleophile would be required to effect the following reactions?
A: a) aqueous NaOH or aqueous KOH Nucleophilic substitution reaction (SN2 mechanism) b) NaOCH3 (sodium…
Q: Which compound will be a major product of the reaction sequence shown below?
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Q: All of the following are true of SN2 reactions except: The rate of the SN2 reaction of a substrate…
A: Sn2 reaction is bimolecular nucleophilic substitution reaction.
Q: List A-D in order of increasing ability of a nucleophile to displace a leaving group in a…
A: a) & b) Aqueous acetone is a protic solvent (the water H-bonds tightly to F-) so iodide will…
Q: 2) Propose a set of reaction conditions to most efficiently carry out the following transformations.…
A: Detail mechanistic pathway is given below to carry out the following conversion with appropriate…
Q: Which of the following could act as a nucleophile?
A: Given:To give which of the following could act as a nucleophile
Q: he Table of Reagents, select those that would be used to carry out the following transformation: NH2…
A: A sequential reaction is given and asked what appropriate reagents are used for this reaction.
Q: Which of the following statements about nucleophilic reactions are generally true ? SN2 reactions…
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Q: Which is the best nucleophile for an SN2? A C Ме Me Li Me Li
A: Factors affecting the nucleophilicity : Nucleophilicity is the tendency of an atom or group of atom…
Q: Why is the following reaction sequence not an efficient approach to the desired product?
A: terminal alkynes contains acidic hydrogens eg: acetylene (ethyne), 1-propyne etc this acidic H…
Q: Identify the stronger nucleophile in each pair of anions.a. Br- or Cl- in a polar protic solventb.…
A: a.Polar protic solvents contain hydrogen atoms bonded to electronegative atoms namely O or N.The…
Q: Nucleophilic aromatic substitution involves the formation of a resonance-stabilized carbanion…
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Q: a. Strong bases are [ Select ] nucleophiles. b. Electron-withdrawing groups nearby a nucleophilic…
A: Bases try to abstract hydrogen whereas nucleophiles attack electron deficit carbon atoms. The groups…
Q: Indicate which of the ff. statements regarding nucleophilicity is incorrect. 1. F- is more…
A: Nucleophilicity is directly proportional to Polarisability. Order of nucleophilic halide :…
Q: Rank the relative reactivity of nucleophiles. The shortest time means fastest reaction, which gets…
A: To arrange the nucleophile in order of reactivity.,
Q: Br2 / N2OH R-CO-NH2 R-NH2 H2O
A: It is an example of Hofmann elimination reaction. Here primary amine formed as the product.
Q: Which of the following is a weak nucleophile? OH- H2O CH3O-
A: We have to predict weak nucleophile .
Q: Each of the following may participate in an elimination reaction, under the proper conditions. a)…
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Q: Write the reagents needed to complete this 1-step synthesis. If multiple, consecutiv reagents are…
A: The given reaction is,
Q: if this react with (CH3)3CO- what is possible product and why sn1 reaction is not possible??…
A: The reaction does not follow the SN1 due to steric hindrance of tertiary butoxide so basically both…
Q: lect which molecule is the better nucleophile in e following pair: Br- or Cl- in H20 СНЗО-or CНЗОН…
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Q: For each pair of molecules click on the one which will undergo an E2 reaction more rapidly when…
A: From given Elimination reaction of E2 is briefly described and each pair is compared accordingly as…
Q: Can you assist with identifying starting donor and acceptor compounds are needed to form the…
A: In this question, we want to identify Donor and Acceptor in Michael Reaction. You can see details…
Q: Which is the strongest nucleophile among the following? CN- , OH-, CH3OH, NH3
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Q: The compound below can be prepared with an alkyl iodide and a suitable nucleophile. Identify the…
A: The given structure of the compound appears as follows: The structural formula of the above…
Q: What is the strongest nucleophile, NH3, CH4, CH3O-, or H2O?
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Q: Rank the nucleophiles in following group in order of increasing nucleophilicity. −OH, Br−, F− (polar…
A: The given groups are -OH, Br-, F- To find: The increasing order of nucleophilicity
Q: Show the mechanism of each reaction by supplying the appropriate curved arrows. Also, satisfy the…
A: For given reactions ,mechanism and other detail is given below.
Q: A set of three nucleophilic displacement reactions is shown below: CH3 SOH CH3CH2ĊCH3 SN1 reaction
A: GIVEN
Q: A nucleophile that adds to the beta carbon of an alpha, beta unsaturated aldehyde or ketone would be…
A: Nucleophile is species which carry negative charge. A soft nucleophile have lower charge density and…
Q: Given the following compounds: Which is the most reactive towards a nucleophile? Which will form a…
A: #1: All the given compounds are carbonyl compounds (aldehydes and ketones). Carbonyl compounds…
Q: Rank these substrates in order of increasing ability to undergo a nucleophilic substitution aromatic…
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Step by step
Solved in 2 steps
- Predict whether the following nucleophiles are excellent nucleophiles, good nucleophiles, or poor nucleophiles based on their structure, and sort them accordingly.Select the best set of reagents for carrying out the following synthesisComplete the following nucleophilic substitution reactions. In each reaction, show all electron pairs on both the nucleophile and the leaving group.
- 2. Draw the structures and explain why CH3CH₂O and CH3CO₂ are good nucleophiles but CH3SO3, water, and alcohols (R-OH) are poor nucleophiles. Propose a 'cutoff' for the amount of negative charge needed to be a good nucleophile. CH3CH₂O CH3CO₂ CH3SO3 H₂O CH₂OHIn a Michael addition, which carbon will the nucleophile add to? H₂C B syd A A B C H4. Draw the structure for the product formed in each of step of the following synthetic sequence. benzene 1. LiAlH4 2. H₂O Cl2, FeCl3 Mg, ether SOCI₂ 1.CO₂ 2 H3O+
- For each of the reactions indicate which reactant is the nucleophile and which is the electrophile.Answer the question below the reaction. ta The reaction above proceeds through which type of mechanism? SN2 SN1 E1 E2 OH + Excess NH4C1 H₂SO4 + H₂OIn order to synthesize R-2-chlorohexane, you would need to use [ [ Select ] as the starting material, [ Select ] as the nucleophile source and [ Select] as the solvent.