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- Insulin and aldosterone play an essential role in the regulation of potassium distribution between the intracellular and extracellular fluid compartments. Discuss the effect of a deficiency in these two hormones on internal potassium distributionRegulation of extracellular potassium is not particularly important because only about two percent of the total body potassium is in the extracellular fluid. TRUE or FALSERigor mortis occurs due to the absence of: Ca++ O Troponin O Phosphate O ATP
- How does moderate to severe COPD (chronic obstructive pulmonary disease) often lead to chronic respiratory acidosis? How might the kidneys compensate for this i.e explain at least 2 mechanisms which the kidney may use to do so - be sure to include hormones, cells involved. If the H+/K+ ATPase is brought into service, how would the plasma K+ concentration be affected? Lastly, how would activation of H+/K+ ATPase counteract or synergize with the actions of aldosterone?The rate at which the Na+K+ pump operates is not constant but is controlled by a combined effect of changes in ICF Na+ concentration and ECF K+ concentration. Do you think the changes in both ICF Na+ and ECF K+ concentration following a series of action potentials in a neuron would accelerate, slow down, or have no effect on the Na+K+ pumps in this cell?Explain the action and significance of the Ca 2+ pump and the Na+/K
- Digoxin, a toxin derived from the foxglove (shown), can be used to treat heart disorders such as atrial fibrillation. Digoxin's mechanism of action is to Inhibit the Na+/K+ ATPase. Which of the following is the most likely side effect of Digoxin treatment? Failure to transport glucose into cells during an extended fast O Failure to transport glucose into cells after after eating a large meal O Enhanced response of muscle cells to Acetylcholine O Failure to transport Cl" out of the cell using direct active transportProlonged strenuous exercise usually leads to anincrease in lactic acid. Given your knowledge ofnormal circulation, explain why it is helpful tohave a cool-down period with mild exercise ratherthan total rest immediately after strenuousexerciseIndividuals with McArdle’s disease often experience a “second wind” resulting from cardiovascular adjustments that allow glucose mobilized from liver glycogen to fuel muscle contraction. Explain why the amount of ATP derived in the muscle from circulating glucose is less than the amount of ATP that would be obtained by mobilizing the same amount of glucose from muscle glycogen.
