The emergence of new cases of polio linked to the oral vaccine had been reported in a number of African and Asian countries, revealing that there are now more children being paralyzed by viruses originating in vaccines than in the wild. Viral contamination of a biological may arise from many factors, from handling to the origin of the materials used in the cell culture. a What could be the reason for the outbreak in those countries? b). D) The method of producing attenuated "live" vaccines involve passing the disease- thiusing virus through a series of cell cultures or animal embryos (typically chick embryos). Explain the procedure in details and cite the reason why the method involve passing a virus through a non-human host?

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Viral Infections

Viruses are abundantly found, minute entities that have genetic material enclosed within a protein coat. The proteinaceous material enclosing the genetic material of the virus is called a capsid. The genetic material could be either DNA (deoxyribonucleic acid) or RNA (ribonucleic acid). A virus is too minute to be looked at with naked eyes and therefore visualized with the help of a microscope. They are acellular entities that require a host for processes, such as replication, transcription, translation and multiplication. Plants, animals, and bacteria act as host wherein the virus reproduce. Viruses cannot multiply outside the host's body and thus are considered nonliving outside the host body.