Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation is shown below. H FAD но R- CH2 -C-C- c-S- COA• || H-C-C -S- CoA Acyl-Co.A dehydrogenase H H Acetyl-CoA Fatty acyl-CoA H. FADH2 R- CH2-C-S-COA Thiolase Fatty acyl-CoA shortened by two carbons COA-SH o 'HO I L | R- CH2-C-C-C-S- CoA но Successive cycles R-CH,- c=C C-S-CoA H. H. B-Ketoaċyl-Co.A trans-A²-Enoyl-CoA NADH + H H,0 H L-Hydroxyacyl-СоA dehydrogenase Enoyl-Co.A hydratase R-CH2 C-C C-S-CoA Ba HO NAD+ L-B-Hydroxyacyl-CoA True O False

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter27: Metabolic Integration And Organ Specialization
Section: Chapter Questions
Problem 17P
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Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation is shown below.
H HO
|| ||
C-C-S – CoA
FAD
но
R-CH2-
C
Acyl-CoA
dehydrogenase
H-C-C -S- CoA
Acetyl-CoA
Fatty acyl-CoA
H
FADH2
- CH2 -
-c-S- CoA
R-
Thiolase
Fatty acyl-CoA
shortened by two carbons
COA-SH
H.
он
Successive cycles
R-CH2-C-C-
-C-S- CoA
R– CH2
C=C-C-S-CoA
H
B-Ketoacyl-Co.A
trans-A²Enoyl-CoA
NADH + H*
H,0
H
H
L-Hydroxyacyl-CoA
dehydrogenase
Enoyl-CoA
hydratase
R- CH,-c-c-C- S-CoA
Но
H
NAD+
L-B-Hydroxyacyl-CoA
True
O False
Transcribed Image Text:Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation is shown below. H HO || || C-C-S – CoA FAD но R-CH2- C Acyl-CoA dehydrogenase H-C-C -S- CoA Acetyl-CoA Fatty acyl-CoA H FADH2 - CH2 - -c-S- CoA R- Thiolase Fatty acyl-CoA shortened by two carbons COA-SH H. он Successive cycles R-CH2-C-C- -C-S- CoA R– CH2 C=C-C-S-CoA H B-Ketoacyl-Co.A trans-A²Enoyl-CoA NADH + H* H,0 H H L-Hydroxyacyl-CoA dehydrogenase Enoyl-CoA hydratase R- CH,-c-c-C- S-CoA Но H NAD+ L-B-Hydroxyacyl-CoA True O False
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Cengage Learning