Refer to the experimental approach (i.e., very briefly describe) and give the results AND conclusions. The answer is incomplete without reference to all the data including controls. (A) To investigate whether the microRNA-25-3p (miR-25-3) plays a role in triple negative breast cancer (TNBC), levels of miR-25-3p in cancer and normal adjacent tissue of 20 patients were determined by RT-qPCR. (B) Levels in "normal" (MCF-10A) and cancer cell lines were determined. A B Relative miR-25-3p expression 2.0 1.5- 1.0- 0.5- 0.0- Normal * HOH Tumor Relative miR-25-3p expression ल № MCF-10A MDA-MB-231 Sum-1315

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Please help with answering this Cancer Biology question. Detailed answers are welcome to aid in understanding.

Refer to the experimental approach (i.e., very briefly describe) and give the results AND
conclusions. The answer is incomplete without reference to all the data including controls.
(A) To investigate whether the microRNA-25-3p (miR-25-3) plays a role in triple negative breast
cancer (TNBC), levels of miR-25-3p in cancer and normal adjacent tissue of 20 patients were
determined by RT-qPCR.
(B) Levels in "normal" (MCF-10A) and cancer cell lines were determined.
A
B
Relative miR-25-3p expression
1.5-
1.0-
0.5-
0.0-
Normal
Tumor
Relative miR-25-3p expression
ल
ल
MCF-10A
MDA-MB-231
Sum-1315
Transcribed Image Text:Refer to the experimental approach (i.e., very briefly describe) and give the results AND conclusions. The answer is incomplete without reference to all the data including controls. (A) To investigate whether the microRNA-25-3p (miR-25-3) plays a role in triple negative breast cancer (TNBC), levels of miR-25-3p in cancer and normal adjacent tissue of 20 patients were determined by RT-qPCR. (B) Levels in "normal" (MCF-10A) and cancer cell lines were determined. A B Relative miR-25-3p expression 1.5- 1.0- 0.5- 0.0- Normal Tumor Relative miR-25-3p expression ल ल MCF-10A MDA-MB-231 Sum-1315
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