In solution, fentanyl is most stable in the pH range 3.5-7.5. What mass of acetic acid and sodium acetate would you need to manufacture 1L of 30mM pH 5.2 acetate buffer that could be used for fentanyl. The pKa of acetic acid is 4.6 and the relative molecular mass (RMM) of acetic acid and sodium acetate are 60 and 82 respectively.

Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter4: Stoichiometry: Quantitative Information About Chemical Reactions
Section4.9: Spectrophotometry
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In solution, fentanyl is most stable in the pH range 3.5-7.5. What mass of acetic acid and sodium acetate would you need to manufacture 1L of 30mM pH 5.2 acetate buffer that could be used for fentanyl. The pKa of acetic acid is 4.6 and the relative molecular mass (RMM) of acetic acid and sodium acetate are 60 and 82 respectively.
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