Hemoglobin S homozygotes who are severely anemic often have elevated levels of 2,3-bisphosphoglycerate (BPG) in their erythrocytes. Is this a beneficial effect? Yes, unless the person homozygous for HbS is pregnant. It might be initially beneficial, since the increased [BPG] will help to deliver more oxygen to the tissues. No, since the increased [BPG] will cause more sickling. This effect is neither beneficial nor harmful: BPG has nothing to do with sickle cell anemia. No, since the increased [BPG] decrease the hydrophobicity of the red blood cell making it more difficult for oxygen to diffuse into the cell.
Hemoglobin S homozygotes who are severely anemic often have elevated levels of 2,3-bisphosphoglycerate (BPG) in their erythrocytes. Is this a beneficial effect? Yes, unless the person homozygous for HbS is pregnant. It might be initially beneficial, since the increased [BPG] will help to deliver more oxygen to the tissues. No, since the increased [BPG] will cause more sickling. This effect is neither beneficial nor harmful: BPG has nothing to do with sickle cell anemia. No, since the increased [BPG] decrease the hydrophobicity of the red blood cell making it more difficult for oxygen to diffuse into the cell.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
Section: Chapter Questions
Problem 2TAHL
Related questions
Question
Select all answers that apply
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap …
Biology
ISBN:
9781285866932
Author:
Lauralee Sherwood
Publisher:
Cengage Learning
Human Physiology: From Cells to Systems (MindTap …
Biology
ISBN:
9781285866932
Author:
Lauralee Sherwood
Publisher:
Cengage Learning