Draw the structure(s) of the major organic product(s) obtained after workup of the following reaction N(CH3)h Ag2SO4/conc. H2SO4 Product exhibits complex aromatic proton NMR absorption 1 eq. Br2 You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material Include counter-ions, e.g., NaT, I, in your submission, but draw them in their own separate sketcher. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner.

Draw the structure(s) of the major organic product(s) obtained after workup of the following reaction N(CH3)h Ag2SO4/conc. H2SO4 Product exhibits complex aromatic proton NMR absorption 1 eq. Br2 You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material Include counter-ions, e.g., NaT, I, in your submission, but draw them in their own separate sketcher. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter13: Substitution

Section: Chapter Questions

Problem 4E

See similar textbooks

Similar questions

Draw the structure(s) of the major organic product(s) of the following reaction. t at 1. lithium diisopropylamide / hexane t 2. 1 eq. CH2=CH-CH2CI ot • You do not have to consider stereochemistry. • Omit products derived from the acidic or basic reagent itself, e.g. HN(i-Pr), derived from N(i- ot t Pr)2". If no reaction occurs, draw the organic starting material. • If substantial starting material is present at the end of the reaction, include it in the products. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate structures with + signs from the drop-down menu. ot t ot
3. Draw the structure of the major organic product that forms in each of the following reactions Specify stereochemistry where appropriate. a) b) c) ð CH₂O Br Br 1) PhyCNa/Ether 2)CH₂l Oso (cat) (CH₂N-O2H₂O pyridine/'BuOH/H₂0 OCH, 1) DIBAL (excess) -78°C -rt/3h 2) MnO₂/ CH₂C 11/3h
1. (cont.) CH3 Cl- -CF3 CH;NH2 (i) H ОН ČH,CH3 CH, 1. PBr,/pyridine (j) ОН 2. NaOH/DMSO 2. Using the given starting material and any necessary reagents indicate how the following syntheses can be carried out. ОН CH;CH,CHCH3 CH,CH,CH,COH OH CH;CH,CHCH3 CH;CH,C=CH .OTS OCH3 CH3 CH3 ОН 3. Propose a mechanism that accounts for the formation of the product shown during the following observed reaction. Be sure to show all intermediates. ОН H+
B3. Write a detailed mechanism for the following Knorr Synthesis 1) (BUO-NO (0.5 equiv) , HCI A .CO2Et C14H21NO4 2) Zn, ACOH
Which synthetic sequence will give the following overall transformation? how? (1) LDA / THF; (2) CH31; (3) H2 / Pd on C a. H2 / Pd on C b. (1) HBr; (2) CH3LI; (3) H2 / Pd on C C. (1) BH3 / THF; (2) H2O2: (3) CH3LI d. (1) Li / NH3liq): (2) CH3I Oe.
iii) vii) 10. For each of the following reactions, provide the structure of the major product and circle the predominant mechanism. Indicate the stereochemistry where necessary. E1 E2 SN1 SN2 E1 E2 SN1 SN2 NaSH DMF H* CH₂OH Br (CH3)3COK (CH3)3COH OH iv) HBr viil) E1 E2 SN1 SN2 E1 E2 SN1 SN2
Give the organic product(s) (structure(s)) for each of the stereochemistry where appropriate. If more than one p to specify which the major product is. Write "N.R.“ for r not have to be balanced. Please make sure your answe correctly!!! a) (Me)2CuLi + Acetone 1) 9-BBN b) (Et)2C=CHCHO 2) HOCH2CH2NH2
Which reagents can be used to achieve synthesis of the indicated target molecule? Conc. KMNO4/ H* / acetone 1) O3/ Zn/H* 2) PCC/CH2Cl2 O 1) Conc. KMNO4 /H* 2) LIAIH4/THF 4) H3O* 1) Conc. KMNO4, 2) HBr, 3) Mg/ether, 4) CO2 O3/ Zn/H*
Draw the structure(s) of the major organic product(s) of the following reaction. H,C. 1. NaOCH3 / CH3OH 2. 1 eq. 2-bromo-2-methylpropane • You do not have to consider stereochemistry. • Omit products derived from the acidic or basic reagent itself, e.g. HN(i-Pr)2 derived from N(i-Pr)2. • If no reaction occurs, draw the organic starting material. • If substantial starting material is present at the end of the reaction, include it in the products. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate structures with + signs from the drop-down menu.
Draw the structure(s) of the major organic product(s) of the following reaction. 1. NaOCH3 / CH3OH H3C CH3 2. 1 eq. 2-bromo-2-methylpropane • You do not have to consider stereochemistry. • Omit products derived from the acidic or basic reagent itself, e.g. HN(i-Pr)2 derived from N(i-Pr),. • If no reaction occurs, draw the organic starting material. • If substantial starting material is present at the end of the reaction, include it in the products. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate structures with + signs from the drop-down menu. Draw the structure(s) of the major organic product(s) of the following reaction. Aqueous NaHCO3 0° C 1 eq. Cl2 • Use the wedge/hash bond tools to indicate stereochemistry where it exists. • If the reaction produces a racemic mixture, draw both stereoisomers. • If no reaction occurs, draw the organic starting material. • Draw one structure per sketcher. Add additional…
1) regio- and stereochemical detail. Draw the major organic product generated in the reaction below. Pay particular attention to CH3 -CH3 KMn04 (warm, conc.) CH3 H
Q16. What are the necessary reagents to perform the following synthesis? Choose the answer from the options below. DG (0) CH3MgBr/ether (1) NaBH4, (2) H3O*(aq) c) H₂, Pt d) (1) CH3MgBr/ether, (2) H3O*(aq) (ii) dilute HCl(aq) conc. H₂SO4(aq) conc. H₂SO4(aq) conc. H₂SO4(aq)