Determine the product and name of the rxn HO 1. Аc-0, AcO-Na+ (A) 2. Н20 Ac20= acetic anhydride AcO'Na*= sodium acetate , Aldol condensation a. b. Perkin reaction C. Cannizaro reaction d. Claisen condensation
Q: REF: 21.5 A What is the product of the following reaction sequence? CH3 1. TSCI 2. (CH3);ONa ? OH (d…
A: Step I : Conversion of OH group into leaving group OTs using TsCl. Step II : using base NaO(CH3)3…
Q: CH H' TH. Na OH CH3
A: The reaction given is aldol reaction.
Q: Consider the aldol condensation reaction shown below. Which products will be formed during this…
A: Answer :- I & III
Q: How do polar protic and aprotic solvents affect the reactivity of enolates ? 2.
A: Enolate ions Enolate formation can be depicted as; α H present near a carbonyl group is abstracted…
Q: An electrophilic addition reaction in which a trans а) isomer gives rise only to a meso product, is…
A:
Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…
A:
Q: 10.Draw the structure of the product of the reagent(s) with the substrate: SOCI,
A: We’ll answer the first question since the exact one wasn’t specified. Please submit a new question…
Q: CH3 NaOH CH3-CH-C-H
A:
Q: In micxed aldol condensation of acetone with excess benzaldehyde in the presence of NaOH. what is…
A: Given a reaction of aldol condensation of acetone with excess benzaldehyde in the presence of NaOH.…
Q: What steps use in the Robinson Annulation?
A: Robinson Annulation is an organic reaction, in which the reaction between methyl vinyl ketones and…
Q: 2. -> 0. Kagent: synthesus, using enolate Meations of a 3.
A: Note: According to our guidelines we are supposed to answer only one question. Kindly repost other…
Q: 1.68 Provide the missing intermediates and final product in the following synthesis. 1. ВН3 THF 2.…
A:
Q: for the following, 1) which bond first breaks with retrosynthesis (ex C6-C7). 2) what product is…
A:
Q: uonpga SULMOIOI au 10 Meo DMSO heat view structure Part 2 out of 2 ow consider the stereochemistry…
A: In the part 1 product is given in the question that is correct. Base methoxy will abstract hydrogen…
Q: 16) Diagram the mechanism of the following Claisen reaction. Is the substrate a nucleophile, base,…
A: Given: Claisen reaction To find: the product and if the substrate is a nucleophile, base,…
Q: For each of the steps in Problem 7.26, determine whether the product can eliminate a leaving group…
A: Hi. Since your question has multiple sub-parts, we will solve first three sub-parts for you. If you…
Q: Q5 If you took a TLC of an Aldol reaction/condensation what would be the order of the spots on the…
A: Applying concept of polarity of molecules and relationship with Rf value .
Q: OH `NH2 OCH3 CI 7. Which would be the least reactive to nucleophiles? 8. Which will react with SOCI2…
A: Acyl derivatives reacts with a variety of nucleophile and because the product cam depend on the…
Q: 6. What is a major product of the reaction sequence shown in the box? CH3 Br, or NBS KCN H20 ? Ilght…
A: N-Bromo succinimide (NBS) is the best reagent for allylic or benzylic bromination. The reaction…
Q: The product in the first reaction is a ? H,SO, of R =R H20
A: The product of a first reaction has to be identified below.
Q: GS Q5 Show all missing reagents and intermediates in the reaction sequence below. Put the…
A:
Q: 1) NaOEt Me OEt 2) H30* Could you show the mechanism please, also how do you know which alpha…
A: Given : We have to write the product for the given reaction.
Q: 54. Stability of the carbocation intermediate in an SN1 reaction: CH,=CHCH-OH ČH, I. II.CH2=CHCH2OH
A:
Q: intermediate product NH, 1 2 6 10 8 9 -1
A: The sequence of reaction to reagent 10 and the role of reagent are express below Reagent 1 :…
Q: 25°C HO. HO. Na* OH (aq) OH (aq) 25°C 85°C aldol
A: Answer:- This question is answered by using the simple concept of chemical reaction of self Claisen…
Q: What is the predicted product of the reaction sequence shown? Et N-H, H* Et PCC
A:
Q: 1) 2 possible enolates can form when using (CH3)3CO– as the base to form the enolate of the ketone…
A: the tert butoxide ion is considered a bulky base 2t abstracs less hindrance 2°∝H that leads to less…
Q: HO2C CH2N2 H H Me., Me Et20 90 & (4 steps) Me., Me Me Me
A: Diazomethane (CH2N2) reacts with carboxylic acid to form methyl ester. CH2N2 abstracts proton from…
Q: ouer give the major produt of thisradica reaction.? 유 AIBN Product? Ph Ph HSn Bu By
A:
Q: || b. Aldol addition of xs H3C-CH2-C-H + OH
A:
Q: Cinnamaldehyde may be synthesized through aldol condensation reaction of two aldehydes Q and R as…
A:
Q: Part 3 out of 3 Grignard reaction: 4I CH,CHO MgBr edit structure Draw the intermediate product…
A:
Q: 20) For the reaction below, a) Draw a chair conformation for the substrate in which the leaving…
A:
Q: EIO 1. 2. он OH OE! 3. NO, 5. ???? OEI Remember - can't use simple enolate enol 7. for SN2 type…
A: Note : First do the retro synthesis. Then plan the synthesis.
Q: A.3: Indicate the type of alkyl halide (1°, 2°,3°), the leaving group (Br or Cl'), and the relative…
A:
Q: Which is the product of the reactuon sequence? P(Ph n-BuLI CH,CH,CH,Br OCH CH2CH он CH,CH2CH…
A: Given reactant molecule is:
Q: tu II it 1ONIlal 1epot. OH ОН О H. A For the "crossed" aldol reaction that lead to product C, did…
A: Aldol condensation is a very important reaction in organic chemistry. This is a condensation between…
Q: онон CHI H* но OH Et;N EIOH Meo OMe Meo OMe Meo OMe Meo- Meo OMe A Meo- OMe mOEt OMe Eto OEt EIo OEt…
A:
Q: Your aldol condensation procedure calls for refluxing vanillin in acetone and NaOH for an hour.…
A: Aldehydes or ketones which consist of alpha-hydrogen react with any strong base such as NaOH to…
Q: 2. (a) What is the major enolate formed in each reaction? Justify your prediction : LDA, THF -78 °C…
A: Carbonyl compound having acidic alpha hydrogen, reacts with base to form enolate ion. The enolate…
Q: Me „CHO CO2E Me + Ph3Ps .CO2E† Me CH2CI2 Me 0: Me Me 40 °C, 60 min, 89 % (3 steps) Me See the Wittig…
A: Wittig reaction is an organic chemical reaction wherein an aldehyde or a ketone is reacted with a…
Q: 25 AN GN WEYOTE
A:
Q: [Roview Topics] [References) Draw the structure of the major organic product of the following…
A:
Q: A.I. Self aldol reaction aldal domor = aldol acceptor : Predict fthe major product and draw the ran…
A:
Q: CH, 0 NaOH CH3-CH-C-H
A:
Q: Ph H,O Ph. The final step in the Edman degradation is the acid-catalyzed rearrangement of the ATZ…
A: From the given reaction, we can see that the given base :A- will abstract a proton thereby making a…
Q: Identify the side product produced in the crossed aldol condensation below. OOH CH,CH,CH,CCHCH,CHCH,…
A:
Q: ppose an efficient synthesis for the given transformation. OH OH is transformation can be performed…
A: Given : We have to carry out the transformation:
Step by step
Solved in 2 steps with 2 images
- What is the major product of this reaction sequence? 1. ELONA/E1OH 2. ВГCH-CH2CH3 (1 ед.) 3. НО", heat 67. b. C d. ОН HO. dl loWhat is the product of this reaction sequence? B. ОН A OB OC OD НО 2. LiAIH4 3. H2O, H, heat ОН _OH H+ D. ОН ? ОНWhich reaction (s) does an anhydride produce? HO. NEl3 CI КОН I. calor OK II NH2 O. IV HO HO. calor III a. Ob., IV Oc. I, II d., II, III, IV
- What is the major product of this reaction sequence? CIck on a letterA through D to answer. 1. EIONA/E1OH 2. BrCH-CH-CHз (1 еq.) 3. H30*, heat A. C. HO В. D.products, including stereochemistry. Exercise 25. Determine the mechanism of nucleophilic substitution of each reaction. Draw the + I CN 1. OCH3 + DMSO Br H CI CH3CH2OH 2.Identify the sequence of reactions that successfully completes the following transformation. Ph A. 1. BH3 2. H₂O₂ / NaOH _3. P, l₂ B. HI, ROOR, hv C. 1. HBr, ROOR, hv 2. Nal, acetone D. Choices A and C Ph
- What types of species are the electrophile and nucleophile in an aldol addition? 1. Nu: ester, E+: carbonyl 2. Nu: carbonyl, E+: carbonyl 3. Nu: carbonyl, E+: ester 4. Nu: ester, E+: ester4. Draw the final major product(s) for each multistep synthesis reaction. H3O* OMe H3PO4 Jones Et,NH reagent H30* PBR3 KOC(CH3)3 1. O3 NABH3CN HO- 2. DMS NH3, H3O* Br KOC(CH3)3 1. ВНз PCC H3O* 2. H2О2, ОН CH2CI2resource from Cengage Learning - Google Chrome ssignment/takeCovalentActivity.do?locator=assignment-take e by the Aldol Condensation (References) OH base + H,0 heat H. H3C H. The aldol reaction is a carbonyl condensation reaction between two carbonyl partners and involves a combination of nucleophilic addition and a-substitution steps. One partner is converted into an enolate ion nucleophile and adds to the electrophilic carbonyl group of the second partner. In the classic aldol reaction, the carbonyl partners are aldehydes or ketones, although aldehydes are more reactive. The product is a B-hydroxy carbonyl compound. In the mixed aldol reaction, the best results are obtained when one of the partners does not have an a-hydrogen. It cannot form an enolate anion and can therefore not undergo self-reaction. The enolizable aldehyde is added slowly to a basic solution of the first aldehyde so that the mixed product is preferentially formed. Under reaction conditions slightly more vigorous…
- Draw the major organic product for each of the hydroboration-oxidation reactions. Disregard stereochemistry. Draw the product of Reaction A. Select Draw Rings More ||||||CH|OB Reaction A. 1. B₂H6 2. H₂O₂ (aq) 3M NaOH Reaction B. 1. B₂H6 2. H₂O₂ (aq) 3M NaOH S 3 Draw the product in reaction B. Select Draw Rings More |||||||||CH|OB Erase Q2Q Erase Q2QWrite the structures for A to C in the following synthesis scheme. ol. or Aldol Condensation H A + 1.(CH3)2 Culi 2. H₂O/H* C 1. CH3MgBr 2. H₂O/ H* BDraw the substitution product that results when CH,CH2CH;CH,Br reacts with each nucleophile. d. "OCH(CH3)2 e. "C=CH f. H20 a. "OH g. NH3 b. "SH h. Nal c. "ČN i. NaNg