Answered: CHO CH;CO," Na* Но Он ОН coumarin…

Science

Chemistry

CHO CH;CO," Na* Но Он ОН coumarin o-hydroxybenzaldehyde

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter19: Carboxylic Anhydrides, Esters, And Amides

Section: Chapter Questions

Problem 19.31P

See similar textbooks

Related questions

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: SOLUTION: Step 1: Pitavastatin (Livalo) is a lipid-lowering agent. It is used in the treatment of…

Q: Draw a stepwise mechanism for the following reaction. .COOH H2SO4 но H20

A: H2SO4 is an acid that usually activates organic compound to generate electron-deficient, cation.…

Q: Draw a stepwise, detailed mechanism for the following reaction. Use curved arrows to show the…

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: Proton abstraction from the acid HCl. Nucleophilic attack on to the carbonyl carbon by the lone…

Q: Draw a stepwise, detailed mechanism for the following reaction. CH3NH2 N-CH3 CH,NH, Cr (excess)

A: When nitrogen atom is bonded with three carbon atom is known as tertiary amine.

Q: Draw a stepwise mechanism for the following reaction. он Cro3 H2SO4, H2O

A: The chromic oxide, CrO3 gets converted into chromic acid, H2CrO4

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: Answer : Step in the synthesis of the anti-inflammatory drug Celebrex is :

Q: Draw a stepwise mechanism for the attached reaction. Your mechanismmust show how both organic…

Q: 5. Provide the missing reagent indicated by "???": Br ???

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: NaO. + NaO Compound A

A: Attack of nucleophile to the carboxyl carbon of ester Loss of leaving group leading to the…

Q: Draw a stepwise, detailed mechanism for the following reaction. он CH30. CH;O. H,SO4 + H20

A: The mechanism can be shown as: Step 1: Protonation of the alcohol in the presence of acid.

Q: Draw a stepwise mechanism for the following substitution. Explain why 2-chloropyridine reacts faster…

A: Given reaction,

Q: Draw a stepwise mechanism for the following Robinson annulation. This reaction was a key step in a…

Q: Draw a stepwise, detailed mechanism for the following reaction. но + H20 H2SO4

A: In organic reaction, ring expansion takes place to form 6 membered rings.

Q: Draw a stepwise, detailed mechanism for the following reaction.

A: In the reaction of the given reactant with CF3COOH, the attack of lone pair of oxygen on the…

Q: Draw a stepwise, detailed mechanism for the dienone–phenol rearrangement, a reaction that forms…

A: Please find below the reaction mechanism.

Q: Me Me, Вос Вос Me

A: We have to Provide a step wise mechanism for the given reaction:

Q: Rank the following sets of compounds by the indicated criteria. A) Rate of reaction with Br/FeBrs…

A: Rate of the electrophilic aromatic substitution reaction depend upon electron density on the…

Q: Proposed a mechanism to determine the final product NEN CIO

Q: NH, H3C CH3

Q: Answer the following question about curcumin, a yellow pigmentisolated from turmeric, a tropical…

A: The enol form is more stable due to the intramolecular hydrogen bonding with nearby oxygen

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: Protonation of oxygen atom takes place in the presence of acid H3O+ Hydrogen atom migrates to…

Q: Devise a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: The diester undergoes Dieckmann reaction in the presence of base to form beta-ketoester. The base…

Q: Draw a stepwise, detailed mechanism for the following intramolecular reaction.

A: SOLUTION: Step 1: The intramolecular ring closure is carried out in the presence of strong acid like…

Q: Draw a stepwise mechanism for the following substitution. Explain why 2-chloropyridine reacts faster…

A: Methoxide ion reacts with imine carbon of 2-chloropyridine to form amide ion.

Q: 1. MeONa, MEOH 2. H3O* workup

A: The goes via enolization at first then intramolecular SN2 reaction followed by quasi-favorskii type…

Q: Draw a stepwise, detailed mechanism for the following reaction.

A: In intramolecular reactions, the reactive sites are present in the same molecule. The simplest…

Q: Draw a stepwise mechanism for the following reaction. The fourmembered ring in the starting material…

A: In the given reaction, the four-membered ring is the starting material and the product is called as…

Q: CH3 -CI OH

A: The given structure is; The name of the above structure is 1-Chloro-1-methyl cyclohexane. Here, -OH…

Q: Draw a stepwise mechanism for the following reaction, which forms the four-membered ring in…

Q: Draw a stepwise, detailed mechanism for the following reaction.

A: The above reaction is a diel's alder reaction in which a diene and and a dienophile undergo [2+4]…

Q: "ropose a mechanism for the following reaction. но H,SO, + H,0

Q: Draw a stepwise, detailed mechanism for the attached reaction.

A: Amines act as bases as well as nucleophiles due to presence of lone pair on the nitrogen atom. On…

Q: Draw a stepwise, detailed mechanism for the attached intramolecularreaction that forms a cyclic…

A: Cyclic ethers are formed when alcohols undergo intramolecular reaction. Strong acid such as sulfuric…

Q: Draw a stepwise mechanism for the following reaction: H,SO, Part 1:

Q: Draw a step wise, detailed mechanism for the following reaction.

A: To find: The detailed mechanism of the given reaction.

Q: Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the…

Q: Draw a stepwise mechanism for the attached reaction.

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the…

Q: a) ホ→ OMe b)

A: Number of functional group is associated with organic compounds which impart specific chemical and…

Q: Draw the detailed reaction mechanism of methyl salicylate to salicylic acid. Show movement of arrows…

A: Here we are required to predict the mechanism for the reaction

Q: Propose a mechanism for the following reaction:

A: In organic chemistry, there is a class of reactions that belongs to rearrangement reactions. This…

Q: Draw a stepwise mechanism for the following reaction. The four-membered ring in the starting…

A: The four membraned ring in the starting material and product is called as beta-lactum ring. DBN is a…

Q: Draw a stepwise mechanism for the attached reaction. (Hint: Conjugateaddition can occur with…

A: Nucleophilic Conjugate addition reaction: The reaction will take place when In α-β unsaturated…

Q: Draw a stepwise mechanism for the following reaction, a key step in thesynthesis of the…

Q: Draw a stepwise mechanism for the following reaction: H,SO, Part 1: A. HSO, B. H,SO, C. H,0 view…

A: The reaction taking place is given as,

Q: S O NaBH4 OLIAIH4 OBH3, THF OLIAIH(O'Bu) 3 OH

A: Organic reactions are those in which organic reactant react to form organic products.

Q: Draw a stepwise, detailed mechanism for the following reaction.

A: Since the reactant is tertiary alkyl halide. Hence it will form a carbocation in intermediate Hence…

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

Coumarin, a naturally occurring compound isolated from lavender, sweet clover, and tonka bean, is made in the laboratory from o hydroxybenzaldehyde by the reaction depicted below. Draw a stepwise mechanism for this reaction. Coumarin derivatives are useful synthetic anticoagulants.

CHO
CH;CO," Na*
Но
Он
ОН
coumarin
o-hydroxybenzaldehyde

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

H3C, CH3 Nefidipine from benzaldehyde and alkene derivative PREOC CO₂Et
Which of the following compounds best dissolve in toluene? so, Na HO но, HO NH, a) b) d)
How many P – O – P bonds are there in cyclotrimetaphosphoric acid?
10)2-chloro propanamine
Draw the organic product formed when the followingcompounds undergo a substitution reaction: (a) acetic acid and1-hexanol; (b) propanoic acid and dimethylamine; (c) ethanoicacid and diethylamine.
Identify the type of amine shown in the molecules. H;C-CH,-N-CH,–CH; CH, H;C-N-CH,-CH; H;C-CH-CH,–CH, ČH; secondary primary tertiary
Sodium borohydride used in the organic lab is a(n) amine carboxylic acid oxidizing agent reducing agent
Eistrogens are female sex hormones, the most potent of which is B-estradiol. OH H,C но B-Estradiol In recent years, chemists have focused on designing and synthesizing molecules that bind to estrogen receptors. One target of this research has been nonsteroidal estrogen antagonists, compounds that interact with estrogen receptors and block the effects of both endogenous and exogenous estrogens. A feature common to one type of nonste- roidal estrogen antagonist is the presence of a 1,2-diphenylethylene with one of the benzene rings bearing a dialkylaminoethoxyl substituent. The first nonsteroidal estrogen antagonist of this type to achieve clinical importance was tamoxifen, now an important drug in the treatment of breast cancer. Tamoxifen has the Z configuration shown here. но NMe, NMeg ? B NMeg ? "NMe, ОН Tamoxifen Propose reagents for the conversion of A to tamoxifen. Note: The final step in this synthesis gives a mixture of E and Z isomers.
Which pesticide doesn't have a halogen functional group?ImazapyrNitisinone2,4,5-Trichlorophenoxyacetic acidSimazineAll of these have a halogen
How harmful Terephthalic acid is paarticularly in human health and environment?
AMIDES Complete the following equations: CH;CHCICOOH + NH2CH2CH3 ----100°C----> CH3CH,CH2COOH + NH3 ----100°C----> C6H12 COONCH; CH2CH3 + H20 ---HEAT/HCI-----> CH;CH;CH,COONHCH2CH; + H20 ---HEAT/NAOH---->
Why is the amine N atom more nucleophilic than the amide N atom in CH,CONHCH,CH,CH,NHCH,?