CF3 -NHNH, НC -CF3 H,NSO,- celecoxib H2NSO,

Introductory Chemistry: A Foundation
9th Edition
ISBN:9781337399425
Author:Steven S. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Donald J. DeCoste
Chapter12: Chemical Bonding
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Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the anti-inammatory drug celecoxib (trade name Celebrex).

CF3
-NHNH,
НC
-CF3
H,NSO,-
celecoxib
H2NSO,
Transcribed Image Text:CF3 -NHNH, НC -CF3 H,NSO,- celecoxib H2NSO,
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The mechanism has to be shown.

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