Past paper question (၁)Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts asa chain terminator.HOCH3AzidothymidineFigure Q10(c)(i) What is the therapeutic use of AZT?(1 marks)(ii) Define the meaning of a prodrug.(1 marks)(iii) Describe the mechanism of action of AZT.(5 marks)

iii) Azidothymidine, commonly known as AZT, is a medication used in the treatment of HIV/AIDS. Its…

Answered: (၁) Azidothymidine (AZT), shown in…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section23.6: Reactions With Acids

Problem 23.9P

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(၁) Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts as a chain terminator. HO CH3 Azidothymidine Figure Q10(c) (i) What is the therapeutic use of AZT? (1 marks) (ii) Define the meaning of a prodrug. (1 marks) (iii) Describe the mechanism of action of AZT. (5 marks)