Is flavopiridol a natural product?

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter21: Lipids
Section: Chapter Questions
Problem 21.45P
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2. Flavopiridol was the first semi-synthetic cyclin-dependent
kinase inhibitor to be tested in clinical trials. Research has
shown that co-administration of flavopiridol with drugs such as
the taxanes had synergistic cytotoxic effects against a variety of
tumour cells.
HO
но,
HO O
1114
CI
2.1 Is flavopiridol a natural product? Explain your answer.
Transcribed Image Text:2. Flavopiridol was the first semi-synthetic cyclin-dependent kinase inhibitor to be tested in clinical trials. Research has shown that co-administration of flavopiridol with drugs such as the taxanes had synergistic cytotoxic effects against a variety of tumour cells. HO но, HO O 1114 CI 2.1 Is flavopiridol a natural product? Explain your answer.
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