A loss-of-function mutation in the ion channel responsible for the generation of end-plate potentials results in a diminished permeability of the ion channel. 1) How would you experimentally test the effect of the mutation on the functional properties of the cell (synapse)? You should discuss the types of postsynaptic responses and physiological parameters you could measure.

A loss-of-function mutation in the ion channel responsible for the generation of end-plate potentials results in a diminished permeability of the ion channel. 1) How would you experimentally test the effect of the mutation on the functional properties of the cell (synapse)? You should discuss the types of postsynaptic responses and physiological parameters you could measure.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 1RE: Conformational changes in channel proteins brought about by voltage changes are responsible for...

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