17. To avoid risk of toxicity, it is desirable to monitor the srrum concentrations of which of the following antibiotics? (A) Coftriaxone (B) Clindamycin (C) Erythromycin (D) Gentamicin (E) Imipenem-cilastatin
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17. To avoid risk of toxicity, it is desirable to monitor the srrum concentrations of which of the following antibiotics?
(A) Coftriaxone
(B) Clindamycin
(C) Erythromycin
(D) Gentamicin
(E) Imipenem-cilastatin
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Solved in 2 steps
- 94. A 45-year-old woman is receiving cyclosporine following a renal transplant. After developing a community-acquired pneumonia, she is treated with an antibiotic. Despite maintaining a constant dose of cyclosporine, her serum concentration of cyclosporine doubles. Concurrent use of which of the following drugs is most likely to lead to this change? OA) Cephalexin B) Erythromycin OC) Penicillin G QD) Tetracycline E) Trimethoprim-sulfamethoxazole49. The bioavailability of drug X after oral administration is 38%. Which of the following best explains this level of systemic bioavailability? A) Adipose distribution B) Hepatic metabolism C) Plasma protein binding D) Pulmonary metabolism E) Renal metabolism13) Which of the following best describes the mechanism of an antiplatelet medication? A) Inhibition of platelet aggregation B) Blocking of sodium channels C) Inhibition of the inflammatory response D) Inhibition of factor X conversion
- 54. Following are used to treat DIC except A) PlateletsB) Packed cellsC) WBCD) cryoprecipitates27. In a life-threatening situation when a therapeutic concentration of a drug is needed immediately, which of the following is the best means for choosing the loading dose? A) Bolus of five times the maintenance dose B) Infusion at five times the normal maintenance rate for 1 half-life C) Maintenance dose times body weight D) Maintenance doses with the dose interval equal to the half-life E) Steady-state plasma concentration times the volume of distribution6. Serum blood of a patient with dislipoproteinemia type I has milky appearance even in fasting. If serum stays at low temperature (4) for several hours, the fatty layer appears on its surface. What are the possible causes of these symptoms? Answer the questions and do the following tasks: a) what compounds of serum blood must be tested in the patient in a biochemical lab? b) what is the possible diagnosis of the discase? c) draw the reaction which does not occur properly in the patient's blood; d) explain how the products of the previous reaction are used in adiposc tissue and heart in a healthy person I hour after meal.
- 5. Which statement regarding the use of rocuronium is true? Don't copy A) It has more rapid onset than vecuronium B) It has the same mechanism of action as succinylcholine C) It is the least cardiac stable neuromuscular blocking agent D) It has a significantly longer duration than vecuronium?HO Acetaminophen is prescribed more frequently in hospitals than aspirin is due to the fact that acetaminophen is NOT IZ CH3 A) An anticoagulant B) An antipyretic C) An anti-inflammatory D) SyntheticAnimal and clinical studies have shown that administration of lactated Ringer’s solution to patients with hypovolemic shock may() A) Increase serum lactate concentration B) Impair liver function C) Improve hemodynamics by alleviating the deficit in the interstitial fluid compartment D) Increase metabolic acidosis E) Increase the need for blood transfusion
- When a patient is receiving long-term NSAID therapy, which drug may be given to prevent the serious gastrointestinal adverse effects of NSAIDs?a )misoprostol (Cytotec)b) metoprolol(Lopressor)c) metoclopramide(Reglan)d) magnesium sulfate3 which of the following drug does not cause thrombocytopenia A) HeparinB) Sulfa containing antibioticC) InterferonsD) Penicillin5. Which statement regarding the use of rocuronium is true? A) It has more rapid onset than vecuronium B) It has the same mechanism of action as succinylcholine C) It is the least cardiac stable neuromuscular blocking agent D) It has a significantly longer duration than vecuronium?