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- 54. The volume of distribution of a drug is 350 L. Which of the following is most likely to account for this volume of distribution? OA) Extensive binding to tissue proteins B) Extensive hepatic metabolism C) Inability to cross the blood-brain barrier D) Low lipid solubility E) Rapid renal excretionWhich of the following is a contraindication to anticoagulant use? A) Recent injury B) Diabetes C) Asthma D) Dizziness Which of the following is an antiplatelet medication? A) Diltiazem B) Labetalol C) Procainamide D) Aspirin A commonly shared action of all antiarrhythmics is that they _____________________. A) Inhibit calcium absorption B) Cause vasoconstriction C) Slow the heart rate D) Prevent bradycardia Which of the following medications is an ACE inhibitor? A) Aspirin B) Labetalol C) Lisinopril D) Simvastatin A Class II antiarrhythmic blocks ____________ channels. A) Potassium B) Beta C) Sodium D) Calcium A potential complication with the administration of a diuretic is ______________________. A) Hypothermia B) Hypernatremia C) Hypokalemia D) Hypoglycemia27. In a life-threatening situation when a therapeutic concentration of a drug is needed immediately, which of the following is the best means for choosing the loading dose? A) Bolus of five times the maintenance dose B) Infusion at five times the normal maintenance rate for 1 half-life C) Maintenance dose times body weight D) Maintenance doses with the dose interval equal to the half-life E) Steady-state plasma concentration times the volume of distribution
- 1 Which of the following is a contraindication to the antiarrhythmic Amiodarone? A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension 2 Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination 3 Which of the following most accurately describes the mechanism of action of a "statin"? A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle 4 Which of the following is an indication to the antiarrhythmic Amiodarone? A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)Please answer the following questions 1) Vd of a drug will be high when it is distributed in the following tissues except-a) Adipose tissueb) Brain and spinal cordc) Skeletal muscle tissued) Visceral fate) Mesentery tissuef) fats covering kidney and spleen 2) In a 2-comp. open model system the rate of drug disposition between compartents follow-a) zero orderb) 1-orderc) 2-rderd) 3-ordere) mixed orderf) none of the above 3) The likely molecular wt. of a drug for oral absorption is-a) no more than 400b) no more than 350c) no more than 550d) no more than 700e) no more than 650f) no more than 500The following items dose in micro-grama) Amlodipine b) Ceftrixone c) Ceftazidime d) Atropine
- The nurse caring for a patient who is receiving betal agonist drug therapy needs to be aware that these drugs cause which effect? a )Increased cardiac contractility b) Decreased heart rate c )Bronchoconstriction d)Increased Gl tract motilityWhich of the following accurately describes the mechanism of action of an ACE inhibitor? A) Vasodilation B) Sodium excretion C) Anticoagulant D) Both A and B A contraindication to ACE inhibitor administration is ____________________________. A) Respiratory Distress B) Chest Pain C) Allergy to Aspirin D) Hypotension Which of the following best describes the mechanism of an antiplatelet medication? A) Inhibition of platelet aggregation B) Blocking of sodium channels C) Inhibition of the inflammatory response D) Inhibition of factor X conversion A contraindication to beta blocker administration is ____________________________. A) Tachycardia B) Simvastatin Allergy C) Bradycardia D) NauseaWhich of the following medications is a beta blocker? A) Hydrochlorothiazide B) Lasix C) Atenolol D) Simvastatin Which of the following is a contraindication to the antiarrhythmic Amiodarone? A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination Which of the following most accurately describes the mechanism of action of a "statin"? A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle Which of the following is an indication to the antiarrhythmic Amiodarone? A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)
- The most important manifestation of acetaminophen toxicity is: Question 11 options: A) metallic taste B) hepatic damage C) abdominal pain D) bloody diarrhea13) Which of the following best describes the mechanism of an antiplatelet medication? A) Inhibition of platelet aggregation B) Blocking of sodium channels C) Inhibition of the inflammatory response D) Inhibition of factor X conversion33) Your patient has a chronic history of congestive heart failure and does not currently have pulmonary edema. Why is administration of a beta blocker beneficial to this patient? A) Beta blockers may help reduce the risk of blood clotting B) Beta blocker administration is not beneficial to this group C) Because beta blocker manufacturers pay you a lot of money to administer them D) Beta blockers minimize the risk of hypertrophic heart disease 34) If the patient in #33 had pulmonary edema, why could beta blocker administration be detrimental? A) The blood pressure could be lowered B) More fluid would back up into the lungs C) It would increase risk of blood clotting D) Beta blocker administration is indicated in this patient