Tissues and differentiation: a) Explain what is meant by determination and differentiation b) Explain the difference between an oncogene and a tumor suppressor gene and describe how they are involved in the development of cancer

Tissues and differentiation: a) Explain what is meant by determination and differentiation b) Explain the difference between an oncogene and a tumor suppressor gene and describe how they are involved in the development of cancer

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter6: Reproduction At The Cellular Level

Section: Chapter Questions

Problem 15CTQ: Explain the difference between a proto-oncogene and a tumor suppressor gene.

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Tissues and differentiation:

a) Explain what is meant by determination and differentiation

b) Explain the difference between an oncogene and a tumor suppressor gene and describe how they are involved in the development of cancer

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Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain the difference between an oncogenic and a tumour suppressor gene and describe how they are involved in the onset of cancer
Describe the genetic changes that inactivate tumor-suppressor genes.
Define the following terms: tumor, neoplasia, anaplasia, metastasis, proto-oncogene, oncogene, and tumor suppressor gene.
explain the difference between benign and malignant tumors?
Differentiate among the terms cancer, tumor, and neoplasm. Note. There is a little confusion about the terms "tumor" and "neoplasm". Think about cancers such as leukemia and other blood cell cancers. Are they tumors?
Explain what is fundamental aberrations in all cancer cells ?
D. What is the best term for a normal INK gene? (tumor suppressor) (inactive tumor suppressor) (oncogene) (proto-oncogene) (oncogene or tumor suppressor) (beats me). E. Suppose you have cells that have permanently active ink protein as in C. The cells also have permanently active E2F or permanently active ras. (Consult texts or handouts for roles of E2F and ras.) E-1. If your cells have active E2F and active ink, then your cells should (grow normally) (fail to grow) grow uncontrollably) (can't predict). E-2. If your cells have active ras and active ink, then your cells should (grow normally) (fail to grow) grow uncontrollably) (can't predict).
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Describe the difference between a tumor suppressor and an oncogene with respect to the actual causes of cancer.
Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the organismal level.
Describe the key characteristics of cancer.
Which of the following is true of tumor suppressor genes? Group of answer choices a) If this gene is overactive, it becomes an oncogene b) If one of the alleles is mutated, there is usually little effect. Two inactivating mutations are usually required for loss of function (recessive mutation). c) If one copy is lost, the gene no longer functions (dominant mutation) d) Tumor suppressors genes usually cause mitosis or cell growth e) Tumor suppressor genes decrease apoptosis