The TPD method measures temperature elevations in a tissue region during a heating pulse and its later temperature decay after the pulse. It is then using the Pennes bioheat equation to perform a curve fitting to determine the local blood perfusion rate. If the TPD probe is placed in the vicinity of very large blood vessel, will the TPD technique provide an accurate measurement of the local blood perfusion in the vicinity of this large blood vessel? Explain briefly. (Hint: Is the Pennes bioheat equation accurate surrounding a large blood vessel?)

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Chapter8: Natural Convection
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The TPD method measures temperature elevations in a tissue region during a heating pulse
and its later temperature decay after the pulse. It is then using the Pennes bioheat equation to perform a
curve fitting to determine the local blood perfusion rate. If the TPD probe is placed in the vicinity of very
large blood vessel, will the TPD technique provide an accurate measurement of the local blood perfusion
in the vicinity of this large blood vessel? Explain briefly. (Hint: Is the Pennes bioheat equation accurate
surrounding a large blood vessel?)
Transcribed Image Text:The TPD method measures temperature elevations in a tissue region during a heating pulse and its later temperature decay after the pulse. It is then using the Pennes bioheat equation to perform a curve fitting to determine the local blood perfusion rate. If the TPD probe is placed in the vicinity of very large blood vessel, will the TPD technique provide an accurate measurement of the local blood perfusion in the vicinity of this large blood vessel? Explain briefly. (Hint: Is the Pennes bioheat equation accurate surrounding a large blood vessel?)
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