The possession of one of two types of earlobes (hanging or attached) is sometimes used to study the inheritance of characteristics in humans. The pedigree shows the different types of earlobes present in three generations. 3 KEY male with hanging earlobes II female with hanging earlobes 5 6 male with attached earlobes female with attached earlobes II Discuss the type of inheritance shown in the pedigree. In your answer, include reference to the alleles involved using standard notation.
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- Question 47 Everyone who inherits the disease causing alleles has some symptoms. multifactorial traits Pleiotropy Polygenic inheritance Incomplete penetrance O Variable expression O Complete penetranceQUESTION 8 Consider the following pedigree. With no other information provided, what is the most likely mode of transmission (or mode of inheritance) of the allele for the unusual trait? sex-linked recessive autosomal recessive autosomal dominant sex-linked dominantQUESTION 5. The pedigree below follows the appearance of a rare autosomal dominant condition resulting in malformation of limbs through a family. What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)? Enter your answer in the form of a fraction without any spaces. e.g., If your answer is “one-fourth”, enter: 1/4
- QUESTION 22 Consider whether the mode of inheritance for each of the pedigrees below is autosomal dominant or autosomal recessive Pedigree I Both pedigrees show autosomal dominant modes of inheritance Pedigree I is autosomal dominant while pedigree II is autosomal recessive O Pedigree I is autosomal recessive while pedigree II is autosomal dominant O Both pedigrees show autosomal recessive modes of inheritance QUESTION 23 A Pedigree II The pedigree below shows the inheritance of an X-linked recessive disorder. B TH QuersQUESTION 10 Consider the following pedigree. With no other information provided, what is the most likely mode of transmission (or mode of inheritance) of the allele for the unusual trait? autosomal dominant sex-linked recessive autosomal recessive O sex-linked dominantQuestion 3 Review Mendelian genetics. Match the term and its description. Each term can only be used once. The two alleles for a heritable character separate (segregate) during gamete formation and end up in different gametes | Choose ) Each pair of alleles segregates independently of any other pair of alleles during gamete formation [ Choose ] An organism with two identical alleles for a character [ Choose ] an organism's physical appearance | Choose ) the breeding the mystery individual with a homozygous recessive individual [ Choose ) > > > > >
- Question 2: Consider the following pedigree, which traces the inheritance of a single-gene hereditary disease. Only individuals that are either affected or normal are shown. In other words, potential heterozygotes are NOT indicated. Assume that there is complete penetrance and no variable expressivity, and no new mutations. 2 II III IV Characterize each of the following modes of inheritance as impossible or possible. Justify your answers. a. Autosomal recessive b. Autosomal dominant C. X-linked recessive X-linked dominant Y-linked Sex-limited Sex influenced, dominant in males Sex influenced, dominant in females Mitochondrial inheritance d. e £. ů h. 1.LABORATORY EXERCISES IN GENETICS a. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Duchenne Muscular Dystrophy? are most likly made op intentence for Duchenne Miscular Rysty Uale b. If couple III-7 and IlI-8 have another child, what is the probability that the child will have Duchenne Muscular Dystrophy? c. If IlI-2 and IlI-7 mated, what is the probability that one of their children would have the disease?The accompanying pedigree is for a rare, but relativelymild, hereditary disorder of the skin.a. How is the disorder inherited? State reasons for youranswer.b. Give genotypes for as many individuals in thepedigree as possible. (Invent your own defined allelesymbols.)c. Consider the four unaffected children of parentsIII-4 and III-5. In all four-child progenies from parentsof these genotypes, what proportion is expected tocontain all unaffected children?(picture added)
- Hi, I'm having trouble with my study guide for my upcoming genetics exam. If someone could please help with work shown and an explanation it would help so much! Thank you!! 2a. The pedigree below represents inheritance of rare condition. What pattern of inheritance is most consistent with the data? Assign alleles to all individuals to support your answer. If an allele is unknown, assign it a ? symbol. NOTE: Individuals whose phenotype or genotype cannot be determined are assumed to be unaffected and homozygous, unless otherwise indicated. 2b. In addition to the alleles you’ve indicated, describe 2 overall features of the pedigree that make it consistent with your chosen form of inheritance. 2c. Based on your mode of inheritance, what is the probability that the child of couple IV-4 x IV-5 will be affected? Show your work. attached is the pedigreeThe accompanying pedigree shows a very unusual inheritance pattern that actually did exist. All progeny areshown, but the fathers in each mating have been omittedto draw attention to the remarkable pattern.a. Concisely state exactly what is unusual about thispedigree.b. Can the pattern be explained by Mendelianinheritance?Question 51 How does an X-linked gene affect the inheritance pattern for a given trait? Edit Format Table 12pt v Paragraph BIUA