After reviewing the reactions of glutamine formation on page 88 (old edition page 90), explain why each of the following statements concerning the last reaction (or Overall reaction) is true. (Select all that apply) Glutamic acid + NH glutamine; AG" =+3.4 kcal/mole; ATP hydrolyzed in 2 steps 1. This endergonic reaction occurs in the cell because glutamic acid is actually converted to glutamine in 2 sequential reactions, both of which are exergonic: a. 1 reaction: Glutamic acid + ATP ghutamyl phosphate + ADP b. 2nd reaction: Glutamyl phosphate + NH<>glutamine + Pi 2. Overall reaction: Glutamic acid+ATP+NH: glutamine + ADP+P; AG -3.9 kcal/mole If all reactants and products were at standard conditions at the beginning of an experiment, after a period of time, the [NH3]/[ADP] ratio would decrease assuming enzyme glutamine synthase is present. If the reaction were written in in reverse, its AGO would be 3.9 kcal/mol. none of the remaining In the cell, it is possible for glutamine to be formed when the [glutamine]/[glutamic acid] ratio is greater than one.

World of Chemistry, 3rd edition
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ISBN:9781133109655
Author:Steven S. Zumdahl, Susan L. Zumdahl, Donald J. DeCoste
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Chapter21: Biochemistry
Section: Chapter Questions
Problem 46A
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After reviewing the reactions of glutamine formation on page 88 (old edition
page 90), explain why each of the following statements concerning the last
reaction (or Overall reaction) is true. (Select all that apply)
Glutamic acid + NH glutamine; AG" =+3.4 kcal/mole; ATP hydrolyzed in 2 steps
1. This endergonic reaction occurs in the cell because glutamic acid is actually converted to glutamine in 2
sequential reactions, both of which are exergonic:
a. 1 reaction: Glutamic acid + ATP ghutamyl phosphate + ADP
b. 2nd reaction: Glutamyl phosphate + NH<>glutamine + Pi
2. Overall reaction: Glutamic acid+ATP+NH:
glutamine + ADP+P; AG -3.9 kcal/mole
If all reactants and products were at standard conditions at the beginning of an
experiment, after a period of time, the [NH3]/[ADP] ratio would decrease assuming
enzyme glutamine synthase is present.
If the reaction were written in in reverse, its AGO would be 3.9 kcal/mol.
none of the remaining
In the cell, it is possible for glutamine to be formed when the [glutamine]/[glutamic
acid] ratio is greater than one.
Transcribed Image Text:After reviewing the reactions of glutamine formation on page 88 (old edition page 90), explain why each of the following statements concerning the last reaction (or Overall reaction) is true. (Select all that apply) Glutamic acid + NH glutamine; AG" =+3.4 kcal/mole; ATP hydrolyzed in 2 steps 1. This endergonic reaction occurs in the cell because glutamic acid is actually converted to glutamine in 2 sequential reactions, both of which are exergonic: a. 1 reaction: Glutamic acid + ATP ghutamyl phosphate + ADP b. 2nd reaction: Glutamyl phosphate + NH<>glutamine + Pi 2. Overall reaction: Glutamic acid+ATP+NH: glutamine + ADP+P; AG -3.9 kcal/mole If all reactants and products were at standard conditions at the beginning of an experiment, after a period of time, the [NH3]/[ADP] ratio would decrease assuming enzyme glutamine synthase is present. If the reaction were written in in reverse, its AGO would be 3.9 kcal/mol. none of the remaining In the cell, it is possible for glutamine to be formed when the [glutamine]/[glutamic acid] ratio is greater than one.
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