709. Explain the signal transduction mechanism for the phosphotidyl inositol second messenger system
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- Explain the function of histidine 57 in the mechanism of chymotrypsin.43. Sequentially list the signal transduction process from ligand binding to biological response for the phospholipase C system. You may use the appropriate abbreviations in your list.156. KNOW THE 5 SECOND MESSENGERS PRODUCED BY G PROTEIN- REGULATED ENZYMES AND THE PURPOSE OF SECOND MESSENGER SYSTEMS.
- Define thymosin-β4,27. Explain the full signal transduction mechanism for intracellular-mediated responses (the actions of lipophilic hormones).Describe the similarities and differences in the structures of GPCRs specific for various ligands including the extracellular , transmembrane , and intracellular domains.
- What other product is generated by phosphoglycerate kinase?There is an unusually high concentration of phosphatidylcholine on the lumenal side of the ER. What structural feature of phosphatidylcholine is responsible for this? Explainhow this structural feature produces this effect72. Explain the basics of the interactions between ligands (chemical messengers) and their receptors. Explain the three factors that influence the magnitude of a target cell's response to ligand binding.