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- What effect will a cAMP inhibitor have on a peptide hormone-mediated signaling pathway? It will prevent the hormone from binding its receptor It will prevent activation of a G-protein It will prevent activation of adenylate cyclase It will prevent activation of protein kinases.2.Explain the difference between steroid hormones and nonsteroid hormones in terms of their actions at target cells.1. Compare the synthesis, storage transport of location of receptors and cellular mechanism of action catecholamine, thyroid, peptide and steroid hormones.
- 5. explain how the concept of cell to cell communication as it applies to the endocrine system. Explain the concept of cell to cell communication as it applies to the nervous system.3. Complete the following table comparing steroid hormones to protein hormones Steroid Hormone Initial Binding Site (i.e. what it initially attaches to and where) Mechanism of Action Example (i.e. name one) Protein Hormone4.What determines plasma concentrations of specific hormones? What determines their effectiveness on target cells and tissues?
- 10. Put the steps involved in generation and release of peptide hormones in the correct order: 1)cleavage into active hormone 2) transport into blood capillary 3)mRNA translation and preprohormone entrance into the ER 4) release signal into ECF 5)vesicular transport into Golgi apparatus 6)signal sequence peptide cleavage into prohormone5. What is the difference between a tropic and nontropic hormone? Be able to describe the pathway of any hormone we discussed from origin to target cells. Be able to describe the function of any hormone we discussed.5. explain how the concept of cell-to-cell communication as it applies to the endocrine system.
- 2. All membrane receptors are blocked in the cell. What hormones actions are kept and why? Write hormones and endocrine glands which secrete them.15. Which of the following is correct about peptide hormones? A. Need transport proteins in blood plasma. B. Transfer messages to an intracellular messenger. C. Can enter cells to activate or repress specific genes. D. Combine with receptors within the target cell cytoplasm.17. The following terms describe how hormones can interact to maintain homeostasis. Define each term and give an example of each situation: Synergism Definition act on the same target cells to exert the same effect Example
