3. A recipient has Ba (III) blood type. There are no C, D and E antigens in blood. What antigens and antibodies content from the named above systems are permissible in donor blood which is to be trasfused to the patient?
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- II. Fill in the Appropriate Information on table 3. 田 Recipient's Antibodies Antibody None Blood Type Antibody Antibodies A &B А A В АВ Donors' Antigens1. Serum levels of which antibody is indicative of recent infection?? which antibody isotypes remains primarily in serum? IgG, IgA, IgE, IgD, IgM1. List as many as possible blood bank serologic tests that are affected by hemolyzed samples (list as many as possible and how) 2. Enumerate and describe the sources of antibodies utilized in the determination of blood group soluble substances.
- 36) Autoantibodies associated with thrombosis in systemic lupus erythematosus are() A Anti-Sm antibody B Anti-SSA antibody C Anti-cardiolipin antibody D Anti-dsDNA antibody E Anti-nRNPantibody5. Read the heparin label and draw a line on the appropriate syringe, indicating the dose. 1E menaject -S ... 6. The client has progressed to a regula diet and is ordered Humulin N 13 unit and Humulin R 6 units subcutaneous 30 minutes ac breakfast, and Humulin N 5 units and Humulin R 5 units subcuta- neous 30 minutes ac dinner. a. How many units will the client re- ceive before breakfast? b. Indicate on the appropriate syringe given the number of units of each insulin required before breakfast. lai l a NDC 0703-3321-91 NDC 10019-176-3910. Following a rattiesnake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later, he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathologic process? A) Anaphylactic reaction ( Dj Delayed hypersensitivity to horse proteins (✔ Formation of antigen-antibody complexes containing horse proteins and/human immunoglobulins Formation of antigen-antibody complexes containing snake venom proteins and horse antibody Systemic reaction to snake venom Senum Sichness туре !!! Суренийнis (CL
- 3. Analyze the table below and identify who can donate blood to whom. Put a check mark in the box if donation is allowed; otherwise leave the box blank. Group A Group B Group AB Group O A B AB Red blood cell type A AB A B Antibodies in plasma AB Antl-B Anti-A None Anti-A and Antl-B Antigens in red blood cell Aand B antigens Aantigen B antigen None1. What are the functions/basic anatomy and physiology of antibodies? Please include citation (s)16. The Type A Transferase enzyme, attaches N-acetylgalactosamine (GalNAc) to H-antigen epitopes; the Type B Transferase enzyme instead transfers galactose (Gal) to the H-antigen. Individuals with Type A blood thus have at minimum one copy of the active Type A Transferase, those with Type B have at minimum one copy of the active Type B Transferase, those with Type AB have one active copy of each, those with Type O have neither. Imagine an AB individual who acquires a mutation in their Type B Transferase gene that allows it to be active with either Gal or GalNAc. Make sure to include a brief justification for your answer to each question below. a. What blood type antigens would this individual express? b. If this individual had a child with a normal O partner, what possible blood type antigens could the child express? c. If this individual had a child with a homozygous dominant B partner (BB), what possible blood type antigens could the child express?
- 1. When the fibrinolytic factors is not regulated by the inhibitors of the fibrinolysis, what will happen? Explain in not more than 2 sentences. 2. Can the complement system act on a non-particulate substance? Why? 3. If the Mononuclear Phagocytic System (MPS) is considered scavengers in the body, what does PS do after fibrinolysis? 4. D-dimer screening test is important in disseminated vascular disorders (DIC) diagnosis. Why is this statement correct? or wrong? 5. Lupus anticoagulants (LA) prolong APTT results. Yes or No? Defend your answer.1. What is an antiserum? 2. What are the potency requirements in an antiserum? 3. What kind of antigen will anti-A detect? Anti-B? 4. Enumerate the common causes of false positive and false negative result in ABO forward grouping? 5. Give the purpose of Blood typing. 6. Cite the biochemical components of the ABO blood group accordingly. 7. Complete the table below Blood type A B 0 AB (positive/pos) for agglutination (negative/neg) for no agglutination Anti-A Anti-B1. Monoclonal antibodies. Their receipt and use in medical practice.